...André Rosentreter; Stergiani Gaki; Claus Cursiefen; Thomas S. Dietlein Purpose: To assess the efficacy of trabeculectomy with a biodegradable Ologen™ implant (OLO) versus mitomycin C (MMC) in patients in a prospective randomized clinical trial. Methods: In the MMC group (15 patients...

...Leonardo Mastropasqua; Paolo Carpineto; Marco Ciancaglini; Lucio Lobefalo; Pier Enrico Gallenga The effectiveness of intraoperative administration of mitomycin C and the occurrence of postoperative complications have been evaluated in 30 white patients with one recurrence of pterygium. The authors...

...Ryo Suzuki The trabeculectomy procedure was modified with the introduction of the Kelly Descemet membrane punch. Using this punch, a few limbal tissue sections (0.25 ×0.30 mm) were easily excised from beneath the scleral flap base. Mitomycin C (MMC) was used. Among the 100 most recent operations...

...Atsuko Fujitani; Seiji Hayasaka; Yuzo Shibuya; Sachiko Noda A 78-year-old woman complained of ocular pain in the right eye. Thirty-three months before, the patient had a pterygium excised and mitomycin C, 0.04%, was instilled 3 times a day postoperatively for 10 days in the right eye. The same...

...Min Kim; So Hyang Chung; Jae Hwan Lee; Hyung Keun Lee; Kyoung Yul Seo Aims: Our purpose was to compare postoperative results of pterygium surgery between mini-flap technique and conjunctival autograft transplantation without application of mitomycin C. Methods: This is a retrospective, comparative...

...Salvatore Cillino; Francesco Di Pace; Alessandra Casuccio; Giovanni Cillino; Gaetano Lodato Aims: To compare the long-term effects of low-dosage mitomycin C (MMC) in both deep sclerectomy (DSMMC) and trabeculectomy (TPMMC) on intraocular pressure (IOP). Methods: Analysis of extended follow-up...

...Altan Atakan Ozcan; Selcuk Sizmaz; Meltem Yagmur Background: To evaluate the efficacy of topical mitomycin C (MMC) for the treatment of conjunctival tumor in a prospective design. Methods: Nine patients (nine eyes) with conjunctival tumor were studied. The patients received topical MMC 0.04% four...

...Yoshiaki Kiuchi; Reiko Sugimoto; Kazuto Nakae; Yoshihiro Saito; Shigeo Ito Background: To assess the efficacy and to determine the risk factors of trabeculectomy with mitomycin C (MMC) in eyes with neovascular glaucoma (NVG) secondary to diabetic retinopathy. Methods: Kaplan-Meier survival analysis...

...Salvatore Cillino; Francesco Di Pace; Alessandra Casuccio; Gaetano Lodato Purpose: To compare IOP behavior after deep sclerectomy (DS) and trabeculectomy with the Crozafon-De Laage Punch (TP), using low-dosage intraoperative mitomycin C (MMC) in both techniques. Methods: The study was a prospective...

...Jen-Chia Tsai; Hsueh-Wen Chang; Chien-Neng Kao; Ing-Chou Lai; Mei-Ching Teng Purpose: We compare the intermediate-term outcome of initial trabeculectomy with adjunctive mitomycin C use versus initial trabeculectomy alone for juvenile primary open-angle glaucoma. Methods: This retrospective...

...Tamer Demir; Burak Turgut; Nuray Akyol; Ibrahim Ozercan; Fatih Ulaş; Ulkü Celiker Purpose: To evaluate the effects of mitomycin C and amniotic membrane transplantation on the modulation of wound healing after glaucoma filtration surgery. Methods: Trabeculectomy was performed in 3 groups of 10...

...Renata Iveković; Zdravko Mandić; Dean Sarić; Zdenko Sonicki The aim of this study was the comparison of recurrence rates of pterygia following different surgical methods. Twenty-one patients were operated by the bare sclera technique, with the application of mitomycin C (0.25 mg/ml for 2 min...

... been used, including drugs and irradiation. Among the drugs used, mitomycin C and 5-fluorouracil are the most prominent. We discuss the background of these agents, the progress in the use of antimetabolites and the research done on these drugs. These agents have been used both intra-operatively...

... or mitomycin C. The bleeding in 1 case resolved spontaneously, whereas the bleeding in the other 2 cases did not resolve and the visual acuity remained poor. Every patient showed markedly delayed retinal circulation. Possible dysfunction of the retinal blood vessels may be responsible for the development...

...Philip P. Chen; Frank M. Basich; Erfan Khadem We investigated the outcome of trabeculectomy with stored mitomycin C (MMC) in a black Caribbean population on the island of Dominica. Ten eyes (9 patients) underwent trabeculectomy with MMC (0.5 mg/ml for 3–6 min) that had been stored for up to 17...

...Ilgaz Sagdic Yalvac; Ayse Nurözler; Canan Kahraman; Remzi Kasim; Sunay Duman The results of primary trabeculectomy with and without mitomycin C (MMC) were evaluated in young glaucoma patients. The patients, 15–40 years of age, were divided into two main groups and two subgroups. In group IA...

...I. Pinilla; J.M. Larrosa; V. Polo; F.M. Honrubia We evaluated the effect of low doses of mitomycin C (MMC) in subconjunctival injection on fibroblast viability. Eighteen rabbits received subconjunctival injections: group 1 was injected with balanced salt solution (BSS), group 2 received MMC 0.025...

...Lina Daugeliene; Tetsuya Yamamoto; Akira Sawada; Yoshiaki Kitazawa We prospectively measured quantitative changes in the crystalline lens after trabeculectomy with mitomycin C. Twenty-four eyes in 24 trabeculectomy cases were consecutively enrolled in the study. The enrollment criteria consisted...

...Holger Mietz; Michael Diestelhorst; A.F.E. Rump; Michael Theisohn; W. Klaus; Günter K. Krieglstein Hypotony and its sequelae are a frequent complication of trabeculectomies performed with mitomycin C (MMC), possibly related to intraocular toxicity of the substance. In an animal model with rabbits...