...-associated retinal diseases such as age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinal vein occlusion compared with control patients. Results: In serum samples, miR-29a-3p and miR-192-5p showed increased expression in patients with neovascular AMD relative to control patients...

...Maria Vittoria Cicinelli; Giulia Gregori; Alessandro Rabiolo; Beatrice Tombolini; Costanza Barresi; Francesco Pignatelli; Rosangela Lattanzio; Francesco Bandello Introduction: The aim of our study was to investigate factors associated with diabetic retinopathy (DR) severity fluctuations in patients...

...) and blood vessel tortuosity (BVT), and the severity of diabetic retinopathy (DR) by using optical coherence tomographic angiography (OCTA). Methods: In this prospective cross-sectional study, 1,282 ocular-treatment-naive patients with type 2 diabetes mellitus (DM) (1,059 without DR and 223 with DR...

...Sílvia Rêgo; Marco Dutra-Medeiros; Filipe Soares; Matilde Monteiro-Soares Purpose: To evaluate the diagnostic accuracy of a diagnostic system software for the automated screening of diabetic retinopathy (DR) on digital colour fundus photographs, the 2019 Convolutional Neural Network (CNN) model...

...Adnan Kilani; Jens U. Werner; Gerhard K. Lang; Gabriele E. Lang Purpose: To characterize preretinal neovascularizations (NV) and their corresponding branching routes in proliferative diabetic retinopathy (PDR) with optical coherence tomography angiography (OCTA) and compare the findings...

...: This study examined the relationship between proliferative diabetic retinopathy (PDR) and serum levels of C-reactive protein, VEGF, TNF-α, and IL-6 inflammatory biomarkers, related to the pathophysiology of diabetic retinopathy. Methods: This cross-sectional, case control study comprised 240 patients...

...Ozlem Dikmetas; Laura Kuehlewein; Faik Gelisken Introduction: The aim of this article was to report on a rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular edema secondary to diabetic retinopathy (DR) and central or branch retinal vein occlusion (CRVO/BRVO...

... eyes with retinopathy. Conclusion: The results demonstrated a positive correlation between aqueous flare levels, an indicator of intraocular inflammation, and microvascular damage demonstrated by OCTA in the early stages of diabetic retinopathy (DR). This finding supports the role of inflammation...

...: A total of 66,923 patients with DM were included. The prevalence of subjects with DM was 3.8% in 2005 and 4.2% in 2014. The most frequent complication was diabetic retinopathy (23.6%, 95% CI: 21.7–25.5%), followed by diabetic nephropathy (14.8%, 95% CI: 14.0–15.6%) and diabetic neuropathy (4.9%, 95% CI...

...Francesco Bandello; Maria Vittoria Cicinelli In the last decades, significant changes have been taking place regarding the pathogenesis of diabetic retinopathy (DR) and the complex mechanisms that eventually lead to the various manifestations of the disease, including diabetic macular edema (DME...

...Kathrine Kleis Tilma; Toke Bek Background: Diabetic retinopathy is characterised by morphological lesions in the retina secondary to disturbances in retinal blood flow. Previous studies have shown that the carbonic anhydrase inhibitor (CAI) dorzolamide can induce immediate dilatation of retinal...

...Veysel Cankurtaran; Merve Inanc; Kemal Tekin; Faruk Turgut Purpose: To evaluate retinal thicknesses and retinal microcirculation in healthy controls and in diabetic patients with or without microalbuminuria. Methods: Eighty-six diabetic patients without diabetic retinopathy (DR) (44...

... using Spectralis HRA + OCT TM . Thickness measurements of individual layers were calculated using papillomacular bundle (PMB), central subfield, and inner- and outer-ring Early Treatment Diabetic Retinopathy Study (ETDRS) grids. Measurements were compared to 45 normal eyes with no known retinal disease...

...Tien Yin Wong; Charumathi Sabanayagam Diabetes is a global public health disease projected to affect 642 million adults by 2040, with about 75% residing in low- and middle-income countries. Diabetic retinopathy (DR) affects 1 in 3 people with diabetes and remains the leading cause of blindness...

...Christian Enders; Franziska Baeuerle; Gabriele E. Lang; Jens Dreyhaupt; Gerhard K. Lang; Max Loidl; Jens Ulrich Werner Objective: To compare typical findings of diabetic retinopathy in optical coherence tomography angiography (OCTA) and fluorescein angiography (FA). Subjects/Methods: 42 patients...

... of diabetic retinopathy (DR). Papers published from January 2015 to August 2018 describing the use of OCTA in diabetes were identified and reviewed through a Medline/PubMed search. OCTA studies suggest that parameters are altered in patients with diabetes in all retinal vascular layers. From all included...

...Renato M. Passos; José Belucio-Neto; Camilla O. Xavier; Eduardo A. Novais; Mauricio Maia; Michel Eid Farah Objective: To compare two different laser strategies of panretinal photocoagulation for diabetic retinopathy. Methods: Single-center, randomized study including 41 eyes treated with 577-nm...

...-dimensional visualization of the retinal and choroidal vascular network without the administration of an intravenous dye. Moreover, a complete morphofunctional assessment may help in defining both the origin and the clinical activity of different vascular diseases such as diabetic retinopathy. 17 02...

... used for screening of vision-threatening diabetic retinopathy. Methods: An ophthalmic photographer at an Aravind Eye Hospital obtained nonmydriatic and mydriatic fundus images from 3 fields in 275 eyes of 155 participants over 13 months using a Smartscope camera (Optomed, Oulu, Finland) and a Topcon...

... of diabetic retinopathy (DR). Methods: The medical charts of 929 eyes of 465 patients who had undergone SD-OCT were reviewed. The number of hyperreflective foci in the vitreous and attached to the retina was determined in the SD-OCT images. Results: Of the 929 eyes, 284 eyes from diabetic patients and 265...