...Maria Vittoria Cicinelli; Giulia Gregori; Alessandro Rabiolo; Beatrice Tombolini; Costanza Barresi; Francesco Pignatelli; Rosangela Lattanzio; Francesco Bandello Introduction: The aim of our study was to investigate factors associated with diabetic retinopathy (DR) severity fluctuations in patients...

... with nonproliferative diabetic retinopathy (NPDR) in a follow-up period of 3 years. Design: This is a 3-year prospective longitudinal study with four annual visits. Participants: This study involved 74 individuals with type 2 diabetes, NPDR, and Early Treatment Diabetic Retinopathy Study grades from 10 to 47, one eye...

...Marc Figueras-Roca; Marta S. Figueroa; Pilar Calvo; Gonzaga Garay-Aramburu; Jesús R. García-Martínez; Ana María Fernández; Aránzazu Pou; Alfredo Adán; the EMUREX Study Group Purpose: To define and develop a model of excellence for the clinical management of diabetic macular edema (DME) patients...

...Fabio Scarinci; Fabiana Picconi; Gianni Virgili; Paola Giorno; Antonio Di Renzo; Monica Varano; Simona Frontoni; Mariacristina Parravano Purpose: To analyze the retinal-choroidal changes in type 1 diabetes mellitus (DM1) patients with no or early signs of diabetic retinopathy (DR). Methods: Seventy...

...Isabelle Aknin; Laurent Melki Observational studies are needed to confirm the long-term efficacy and safety of Ozurdex® intravitreal implant in real life. Among 29 patients with persistent diabetic macular edema (DME), of whom 14 (48%) patients did not have any previous treatments and 22 (76%) any...

...Sebastien Guigou; Stephan Pommier; Franck Meyer; Christian Hajjar; Pierre Yves Merite; Eric Parrat; Herve Rouhette; Olivier Rebollo; Frederic Matonti Purpose: To evaluate the efficacy and safety of intravitreal implant of dexamethasone (Ozurdex®) in diabetic macular edema (DME). Methods...

...Maria José Simões; Conceição Lobo; Conceição Egas; Sandrina Nunes; Susana Carmona; Miguel Ângelo Costa; Tânia Duarte; Luísa Ribeiro; Carlos Faro; José G. Cunha-Vaz Purpose: To explore phenotype-genotype correlations that may contribute to a better understanding of diabetic retinopathy (DR...

...Jun Zeng; Baihua Chen Diabetic retinopathy (DR), which arises as a result of an increasing incidence of diabetes mellitus, has gradually become a common disease. Due to its complex pathogenesis, the treatment means of DR are very limited. The findings of several studies have shown that instituting...

... diabetic macular edema (DME). Methods: Retrospective review of the medical records of 58 patients with decreased visual acuity, due to refractory DME, who underwent a single injection of Ozurdex between November 2010 and January 2012, at the Instituto de Microcirurgia Ocular, Barcelona, Spain. Results...

...Chien-Chia Su; Chang-Hao Yang; Po-Ting Yeh; Chung-May Yang Purpose: To evaluate the clinical characteristics and surgical outcome of macular tractional retinoschisis (TRS) as compared with tractional retinal detachment (TRD) in proliferative diabetic retinopathy (PDR). Methods: This retrospective...

...Ilaria Zucchiatti; Rosangela Lattanzio; Giuseppe Querques; Lea Querques; Claudia Del Turco; Maria Lucia Cascavilla; Francesco Bandello Purpose: To evaluate the effects of a single injection of Ozurdex over 6 months in eyes with persistent diabetic macular edema (DME). Methods: In this retrospective...

...Ronald C. Gentile; Tatyana Milman; Dean Eliott; Juan M. Romero; Steven A. McCormick Aims: To describe 2 cases of diffuse diabetic macular edema (DME) after diabetic vitrectomy caused by a taut internal limiting membrane (ILM), with clinicopathological correlation. Methods: Interventional case...

...Ozgur Yalcinbayir; Oner Gelisken; Berkant Kaderli; Remzi Avci Purpose: To compare the efficacy of intravitreal and sub-Tenon (ST) posterior triamcinolone injection in the treatment of bilateral diabetic diffuse macular edema (DDME). Methods: 28 eyes of 14 diabetic patients with bilateral DDME were...

...José G. Cunha-Vaz The medical treatment of retinopathy in type-2 diabetes should be considered as a major component in the overall management of diabetic retinal disease. It is clear that specific and timely interventions, such as glycemic and blood pressure control, are the basis for good...

...Giuseppe Ravalico; Daniele Tognetto; Mariantonietta Palomba; Sergio Calderini; Odilla Vattovani The corneal endothelium in diabetics is particularly susceptible to surgical trauma. This is related to the presence of morphological alterations of endothelial cells and to a supposedly concomitant...

...Satoshi Ishikawa; Thouria Bensaoula; Shigekazu Uga; Kazuo Mukuno The ultrastructure of the iris muscles and innervating nerves in patients with diabetes mellitus and approximately age-matched controls was examined by electron-microscopy. The specimens were obtained during cataract surgery...

...M. Fontana; G. Verriest Fluoangiography causes in diabetics a temporary increase of the number of errors when reading Birch and SPP II pseudoisochromatic plates, especially in case of macular edema and for tritan plates. Other experiments show that this change is more due to an increased filter...

...Marjorie A. Mosier; Suhasini S. Deshmukh We measured retinal threshold sensitivity via automated computerized static perimetry in predetermined meridians in euglycemic diabetic subjects and in the same subjects during insulin-induced hypoglycemia. During periods of reduced blood glucose levels...

...Rainer Hans Straub; Andreas Jeron; Lothar Kerp Seventy-seven diabetics with a duration of the disease ranging from 2 to 55 years (average 18.5 years) were studied with infrared videopupillometry. The prevalence of diabetic autonomic neuropathy at the pupillary control system (pANP) was studied...

...G.D. Roversi; E. Giavini Congenital cataract occurs in 90–95% of diabetic rat fetuses. The pathogenetic mechanism is triggered by fetal hyperglycemia and presents the following steps: (1) a high glucose concentration in the lens; (2) reduction of glucose to sorbitol by aldose reductase; (3...