Purpose: Epiretinal membrane is a macular disorder leading to metamorphopsia and decreased visual acuity. The aim of the present study was to assess the possible effects of air tamponade, balanced salt solution (BSS), and combined phacoemulsification on functional and anatomical outcomes. Procedures: This prospective exploratory analysis included 72 eyes with idiopathic epiretinal membranes, scheduled to undergo 23-G pars plana vitrectomy with membrane peeling. Air tamponade or BSS was used in all cases. Optical coherence tomography (OCT) imaging was performed intraoperatively, and follow-up including visual acuity testing and OCT measurements was conducted until 3 months postoperatively. Results: Mean best-corrected visual acuity improved between +2.1 and +3.1 letters, and mean central subfield thickness of the macula decreased between –29.6 and –76 µm in the examined groups, without significant differences between the air tamponade and BSS groups. There was no significant difference in the presence of intraretinal cystoid changes between the groups. Conclusions: The use of air tamponade did not show any significant differences in the anatomical and functional postoperative results compared to BSS. Furthermore, phacovitrectomy did not result in significantly more intraretinal cystoid changes 3 months after surgery.

1.
Mitamura
Y
,
Hirano
K
,
Baba
T
,
Yamamoto
S
.
Correlation of visual recovery with presence of photoreceptor inner/outer segment junction in optical coherence images after epiretinal membrane surgery
.
Br J Ophthalmol
.
2009
Feb
;
93
(
2
):
171
5
.
[PubMed]
0007-1161
2.
Oster
SF
,
Mojana
F
,
Brar
M
,
Yuson
RM
,
Cheng
L
,
Freeman
WR
.
Disruption of the photoreceptor inner segment/outer segment layer on spectral domain-optical coherence tomography is a predictor of poor visual acuity in patients with epiretinal membranes
.
Retina
.
2010
May
;
30
(
5
):
713
8
.
[PubMed]
0275-004X
3.
Shimozono
M
,
Oishi
A
,
Hata
M
,
Matsuki
T
,
Ito
S
,
Ishida
K
, et al.
The significance of cone outer segment tips as a prognostic factor in epiretinal membrane surgery
.
Am J Ophthalmol
.
2012
Apr
;
153
(
4
):
698
704
.
[PubMed]
0002-9394
4.
Govetto
A
,
Virgili
G
,
Rodriguez
FJ
,
Figueroa
MS
,
Sarraf
D
,
Hubschman
JP
.
Functional and anatomical significance of the ectopic inner foveal layers in eyes with idiopathic epiretinal membranes: surgical results at 12 months
.
Retina
.
2017
;
•••
:
[PubMed]
0275-004X
5.
Frisina
R
,
Pinackatt
SJ
,
Sartore
M
,
Monfardini
A
,
Baldi
A
,
Cesana
BM
, et al.
Cystoid macular edema after pars plana vitrectomy for idiopathic epiretinal membrane
.
Graefes Arch Clin Exp Ophthalmol
.
2015
Jan
;
253
(
1
):
47
56
.
[PubMed]
0721-832X
6.
Leisser
C
,
Hirnschall
N
,
Hackl
C
,
Döller
B
,
Varsits
R
,
Ullrich
M
, et al.
Risk factors for postoperative intraretinal cystoid changes after peeling of idiopathic epiretinal membranes among patients randomized for balanced salt solution and air-tamponade
.
Acta Ophthalmol
.
2018
Jun
;
96
(
4
):
e439
44
.
[PubMed]
1755-375X
7.
Mylonas
G
,
Sacu
S
,
Deák
G
,
Dunavoelgyi
R
,
Buehl
W
,
Georgopoulos
M
, et al.;
Macula Study Group Vienna
.
Macular edema following cataract surgery in eyes with previous 23-gauge vitrectomy and peeling of the internal limiting membrane
.
Am J Ophthalmol
.
2013
Feb
;
155
(
2
):
253
259.e2
.
[PubMed]
0002-9394
8.
Miyake
K
,
Mibu
H
,
Horiguchi
M
,
Shirasawa
E
.
Inflammatory mediators in postoperative aphakic and pseudophakic baboon eyes
.
Arch Ophthalmol
.
1990
Dec
;
108
(
12
):
1764
7
.
[PubMed]
0003-9950
9.
Bucci
FA
 Jr
,
Waterbury
LD
.
Prostaglandin E2 inhibition of ketorolac 0.45%, bromfenac 0.09%, and nepafenac 0.1% in patients undergoing phacoemulsification
.
Adv Ther
.
2011
Dec
;
28
(
12
):
1089
95
.
[PubMed]
0741-238X
10.
Hwang
HS
,
Ahn
YJ
,
Lee
HJ
,
Kim
MS
,
Kim
EC
.
Comparison of macular thickness and inflammatory cytokine levels after microincision versus small incision coaxial cataract surgery
.
Acta Ophthalmol
.
2016
May
;
94
(
3
):
e189
94
.
[PubMed]
1755-375X
11.
Liu
YC
,
Setiawan
M
,
Ang
M
,
Yam
GHF
,
Mehta
JS
: Changes in aqueous oxidative stress, prostaglantins, and cytokines: Comparison of low-energy femtosecond laser-assisted cataract surgery versus conventional phacoemulsification. J Cataract Refract Surg
2018
;S0886-3350(18)30857
12.
Leitritz
MA
,
Ziemssen
F
,
Voykov
B
,
Dimopoulos
S
,
Zobor
D
,
Bartz-Schmidt
KU
, et al.
Early postoperative changes of the foveal surface in epiretinal membranes: comparison of 23-gauge macular surgery with air vs. balanced salt solution
.
Graefes Arch Clin Exp Ophthalmol
.
2014
Aug
;
252
(
8
):
1213
9
.
[PubMed]
0721-832X
13.
Saghaei
M
,
Saghaei
S
.
Implementation of an open-source customizable minimization program for allocation of patients to parallel groups in clinical trials
.
J Biomed Sci Eng
.
2011
;
4
(
11
):
734
9
. 1937-6871
14.
Leisser
C
,
Hackl
C
,
Hirnschall
N
,
Luft
N
,
Döller
B
,
Draschl
P
, et al.
Visualizing macular structures during membrane peeling surgery with an intraoperative spectral-domain optical coherence tomography device
.
Ophthalmic Surg Lasers Imaging Retina
.
2016
Apr
;
47
(
4
):
328
32
.
[PubMed]
2325-8160
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.