Purpose: To assess the correlation between dry eye and pterygium. Methods: Tear breakup time (BUT), Schirmer test with/without anesthesia and tear function index were evaluated in both eyes of patients with unilateral pterygium. Results: Tear BUT, was shortened significantly in the eye with pterygium. The Schirmer test with anesthesia was shortened and the tear function index was decreased in the eye with pterygium with marginal significance. Conclusion: There is a correlation between pterygium formation and shortened BUT. Unstable tear film may contribute to the initiation of pterygium.

Keywords:
Pterygium, Dry eye, Tear breakup time, Schirmer test, Tear function index
1.
Coroneo MT: Pterygium as an early indicator of ultraviolet insolation: A hypothesis. Br J Ophthalmol 1993;77:734–739.
2.
Moran DJ, Hollows FC: Pterygium and ultraviolet radiation: A positive correlation. Br J Ophthalmol 1984;68:343–346.
3.
Taylor HR, West SK, Rosenthal FS, Munoz B, Newland HS, Emmett EA: Corneal changes associated with chronic UV irradiation. Arch Ophthalmol 1989;107:1481–1484.
4.
Tan DT, Lim AS, Goh HS, Smith DR: Abnormal expression of the p53 tumor suppressor gene in the conjunctiva of patients with pterygium. Am J Ophthalmol 1997;123:404–405.
5.
Xu K, Yagi Y, Toda I, Tsubota K: Tear function index. Arch Ophthalmol 1995;113:84–88.
6.
Rajiv SM: Pterygium and drye eye – A clinical correlation. Ind J Ophthalmol 1991;38:15–16.
7.
Pandey DJ, Mishra VK, Singh YP, Kumar A, Pandey DN: Quantitative and qualitative estimation of tear in pterygium. Ind J Ophthalmol 1984;32:373–377.
8.
Taylor HR: Studies on the tear film in climatic droplet keratopathy and pterygium. Arch Ophthalmol 1980;98:86–88.
9.
Biedner B, Biger Y, Rothkoff L, Sachs U: Pterygium and basic tear secretion. Ann Ophthalmol 1979;11:1235–1236.
10.
Gillette TE, Allansmith MR: Lactoferrin in human ocular tissues. Am J Ophthalmol 1980;90:30–37.
11.
Shimmura S, Suematsu M, Shimoyama M, Tsubota K, Oguchi Y, Ischimura Y: Subthreshold UV radiation-induced peroxide formation in cultured corneal epithelial cells: The protective effects of lactoferrin. Exp Eye Res 1995;63:519–526.
© 2001 S. Karger AG, Basel
2001
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