A 46-year-old man complained of a painless mass in the left upper eyelid. At age 51 years, the patient complained of dull pain in the left eye and diplopia. His left intraocular pressure had increased to 33 mm Hg. No proptosis was noted. The nontender mass in the eyelid was palpable. Computed tomography showed a mass anterior to the orbital rim compressing the globe. The lesion was removed en bloc by a transconjunctival approach. Histopathologic examination of the excised mass showed myxomatous stroma and highly cellular epithelial areas. Postoperatively, the left intraocular pressure normalized. To our knowledge, benign pleomorphic adenomas arising from the palpebral lobe of the lacrimal gland associated with elevated intraocular pressure, as demonstrated in our patient, may be rare.

1.
Ni C, Cheng SC, Dryja TP, Cheng TY: Lacrimal gland tumor: A clinicopathological analysis of 160 cases. Int Ophthalmol Clin 1982;22:99–120.
2.
Rose GE, Wright JE: Pleomorphic adenoma of the lacrimal gland. Br J Ophthalmol 1992;76:395–400.
3.
Murphy MB, Rodrigues MM: Benign mixed tumor of the (palpebral) lacrimal gland presenting as a nodular eyelid lesion. Am J Ophthalmol 1974;77:108–111.
4.
Okamoto T: Benign mixed tumor of the palpebral lobe of lacrimal gland. Jpn Rev Clin Ophthalmol 1974;68:918–922.
5.
Soushi S, Kimura C: Benign mixed tumor of the palpebral lacrimal gland presenting as nodular eyelid lesion. Jpn Rev Clin Ophthalmol 1981;75:2061–2064.
6.
Auran J, Jacobiec FA, Krebs W: Benign mixed tumor of the palpebral lobe of the lacrimal gland. Clinical diagnosis and appropriate surgical management. Ophthalmology 1988;95:90–99.
7.
Parks SL, Glover AT: Bengin mixed tumors arising in the palpebral lobe of the lacrimal gland. Ophthalmology 1990;97:526–530.
8.
Saito Y, Saito N, Ozawa K, Takeo H, Matsuhashi M, Komoto M, Kameda N, Kawamura S: A case of pleomorphic adenoma of lacrimal gland origin presenting as lid tumor. Folia Ophthalmol Jpn 1992;43:649–652.
9.
Riley FC, Henderson JW: Report of a case of malignant transformation in benign mixed tumor of the lacrimal gland. Am J Ophthalmol 1970;70:767–770.
10.
Perzin KH, Jakobiec FA, Livolsi VA, Desjardins L: Lacrimal gland malignant mixed tumors (carcinomas arising in benign mixed tumors): A clinico-pathologic study. Cancer 1980;45:2593–2606.
11.
Emori M, Hayasaka S, Setogawa T, Miyakuni Y, Fukuma A: Recurrent mixed tumor of the right lacrimal gland causes acute contralateral visual loss. Ophthalmologica 1991;202:138–141.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.