In a retrospective study of 13 patients with complaints of chromatopsia, the history, clinical picture and theory of color adaptation suggest a relatively rapid change in color perception leading to a temporary imbalance of the color vision mechanism. Except for quickly formed absorption systems the mechanism of chromatopsia is not understood, in part because a given presumed disease condition gives rise to a variety of chromatopsias. Surprisingly the authors observed a relatively high incidence of retinal edema in subjects with color distortion.

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