The authors refer to the experiences with the treatment of glaucoma with isoglaucon of 6 months’ duration. The intraocular pressure and the frequency of droppings during the entire period of examination were statistically significantly lower (p < 0.01) in comparison to the starting values. Neither the visus nor the range of the visual field changed. No statistically significant difference between the starting value for blood pressure and the systolic-diastolic difference during the treatment with isoglaucon ( > 0.05) could be determined. For 3 of the 29 patients the treatment with isoglaucon had to be discontinued; these 3 patients were later operated upon.