...Ilyse Kornblau; Nikolas S. Hopkins; Benjamin A. King; Andy Wiles; Enrique Izaguirre; Feng Liu-Smith; Matthew Wilson Introduction: Juxtapapillary uveal melanomas limit plaque brachytherapy treatment using the standard 2 mm margin and are often excluded from prospective studies thus limiting data...

..., focusing on intraocular tumors. Methods: Articles containing “uveal melanoma” (UM), “retinoblastoma” (Rb), “primary intraocular lymphoma” (PIOL), “choroidal metastasis” (CM), and articles in Ocular Oncology and Pathology (OOP) were searched on PubMed and author names obtained. Leadership/awards from 4...

...Yehonatan Weinberger; James Bena; Arun D. Singh Introduction: Since 2003, using the Surveillance, Epidemiology, and End Results (SEER) database, epidemiological aspects of uveal melanoma have been reported. The aim of this study was to update trends in incidence, treatment, and survival of uveal...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Uveal melanoma Brachytherapy Ocular oncology Irradiation While...

...Michael C.Y. Tang; Lisa Klaassen; Marina Marinkovic; T.H. Khanh Vu; Gregorius P.M. Luyten; Carien L. Creutzberg; Martijn Ketelaars; Jan-Willem M. Beenakker Introduction: Ruthenium-106 brachytherapy is a primary treatment for uveal melanoma (UM), the most common intra-ocular malignancy in adults...

...Disorn Suwajanakorn; Anne Marie Lane; Frances Wu; Evangelos S. Gragoudas; Ivana K. Kim Introduction: This study evaluated the association between gene expression profiling (GEP), PRAME (preferentially expressed antigen in melanoma), and regression rate of uveal melanoma after proton beam...

...Florian H. Guillot; Audra K. Miller; Misty Kosydar; Erin Kaya; Brandon Merz; Christina Binder; Jenna M. Kahn; Alicia J. Johnson; Alison H. Skalet Introduction: Vision loss remains a significant concern for patients undergoing radiation treatment for uveal melanoma. Herein, we identify predictors...

... the demographic data, clinical features, and management outcomes of patients with uveal melanoma (UM) in a single tertiary center in Egypt. Methods: This is a single-center retrospective case series. Patients with UM who were managed at Cairo University Ocular Oncology Service between January 2019 and December...

.... Uveal melanoma Subretinal exudation Hard exudates Choroidal biopsy Optical coherence tomography Uveal melanoma is the most frequent primary intraocular tumour in the adult population, with the age-adjusted incidence being 5.1 per million [ 1 ]. The choroid is the most common presentation...

...Talisa E. de Carlo Forest; Scott C.N. Oliver Introduction: The aim of the study was to describe and evaluate characteristics of ocular tumor lysis syndrome (OTLS) in eyes with uveal melanoma. Methods: Retrospective chart review of all patients with OTLS at the University of Colorado from 2009...

...Raquel Benavides; Ricardo Mejías; Alejandro Blanco; Luis Bermudez-Guzman Introduction: Uveal melanoma is the most common primary intraocular malignancy in adults, affecting primarily the choroid of the eye. Plaque brachytherapy is the most common procedure for the treatment of small choroidal...

...Matthew Gillam; Glenn Ace Fenech; Oliver Chadwick; Jonathan Nairn; Vikas Chadha; Julie Connolly; Oliver Cram; Wilma Kincaid; Paul Cauchi Introduction: Proton beam therapy (PBT) is an effective treatment option for uveal melanomas. Following treatment, it may take many months for the tumour...

... was typically given at plaque removal, and thereafter at 3- to 4-month intervals for a maximum of 3 sessions. TTT is typically delivered using an 810 nm diode laser at 200–1,000 mW with a 1.2–5 mm spot for 1–10 min. Uveal melanoma Plaque brachytherapy Cancer Eye Uveal melanoma (UM) is the most...

...Kushal U. Agrawal; Nicholas E. Kalafatis; Konica Singla; Sara E. Lally; Carol L. Shields Purpose: The aims of this study were to study use of tissue glue instead of conventional suturing and to secure I-125 plaque in human eyes with uveal melanoma. Methods: We studied 6 patients with choroidal...

... Oncology Iris nevus Iris melanoma Fluorescein angiography Uveal melanoma Intrinsic vessels Determining the nature of iris melanocytic tumors based on clinical exam alone remains challenging and may require an extended period of follow-up or biopsy to arrive at an accurate diagnosis [ 1 ]. Even...

... true growth is imperative. We performed a retrospective review of patients treated with I-125 brachytherapy for choroidal melanoma at our institution to study this phenomenon. Methods: Records were reviewed for all patients undergoing plaque brachytherapy for uveal melanoma for a 5-year period ( N...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Ruthenium-106 (Ru-106) brachytherapy is commonly utilised for suitable small to medium-sized uveal melanomas [ 1...

...Patrícia M. Pereira; Ana Luís; Maria José Passos; Emanuel Gouveia Introduction: Uveal melanoma (UM) is a rare condition accounting for only 5% of all primary melanoma cases. Still, it is the most frequently diagnosed primary intraocular malignant tumor in adults. UM is an aggressive malignancy...

... secondary to radiotherapy for uveal melanoma in those that failed intravitreal bevacizumab treatment. Methods: A case series of 30 patients with a mean age of 57 ± 15 years with radiation retinopathy were enrolled. Visual acuity (VA) and central foveal thickness (CFT) responses to therapy were assessed...

... and plotted for the GEP class 1 subgroups. Median follow-up of patients who were still alive without metastasis on the date of data analysis was 100.5 months for the GEP 1A patients and 97.2 months for the GEP 1B patients. Results: The actuarial 5-year rate of uveal melanoma metastasis was 10.8% (std. error...