...Frederick A. Jakobiec; Edith R. Reshef; Lina Ma; Martin K. Selig; Daniel R. Lefebvre; Anna M. Stagner An 88-year-old man presented with diplopia, limitation of extraocular movements, and a firm palpable mass in the superolateral orbit. Biopsy revealed a sclerosing signet ring cell carcinoma...

... and retroperitoneum and rarely identified in the orbit. Diagnosis of ALT/WDL can be challenging due to its frequent morphologic overlap with benign adipose lesions and other more aggressive liposarcoma subtypes, including myxoid liposarcoma. We describe a 26-year-old female with a history of hereditary retinoblastoma...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Leiomyosarcoma Conjunctival tumor Limbus Eye Orbit Soft tissue tumor Leiomyosarcomas are mesenchymal neoplasms, recapitulating smooth muscle cell differentiation...

...: Clinical, imaging, and histopathological findings are presented, with a literature review on regressing ocular tumors. Results: Our first patient was a 79-year-old man who presented with a 10-month history of progressive left upper eyelid ptosis caused by an eyelid tumor with orbital involvement...

...Jasmine H. Francis; Christopher A. Barker; Vivian T. Yin; Richard D. Carvajal; Paul Chapman; David H. Abramson; Y. Pierre Gobin Background/Aims: The treatment of orbital melanoma poses a management challenge. This case explores the delivery of high-dose melphalan to an orbital recurrence of uveal...

... a predilection for orbital metastases. They can occasionally contain regions with prominent vacuolated cytoplasm and minimal nuclear atypia, which mimic benign histiocytic lesions. Differentiating nonneoplastic, primary neoplastic, and metastatic histiocytoid lesions involving the periorbita can be challenging...

...Bifica Lyngdoh; Jaya Mishra; Biswajit Dey; Caleb Harris; Arindom Kakati; Zachariah Chowdhury; Rintu Marak; Evarisalin Marbaniang Orbital location of extraskeletal osteosarcoma is extremely rare with only 4 cases reported so far in the English literature. We present the case of a 32-year-old female...

...Giancarlo A. Garcia; Andrew E. Choy; Anton N. Hasso; Don S. Minckler Purpose of the Study: Orbital meningiomas are typically benign tumors, most commonly originating from the dura of the sphenoid wing or the optic nerve sheath. Procedures: We describe an unusual case of a malignant meningioma...

...Masoomeh Eghtedari; Amir Reza Farsiani; Mohammad Reza Bordbar Rhabdomyosarcoma (RMS) is the most common malignant tumor of the orbit in children, but it is rarely present at birth. We report a large congenital orbital RMS with intracranial extension in a newborn baby. A newborn baby girl...

...Frederick A. Jakobiec; Natalie Homer; Fouad R. Zakka; Hugh D. Curtin; Aaron Fay Objective: To distinguish between a multifocal orbital lymphoid tumor and a major simulator represented by a diffuse lymphaticovenous malformation. Methods: We performed a comparison of clinical and radiographic...

..., hyperpigmented lesion involving the orbit and intracranial cavity diagnosed as PEM. The case is unique given the young age and the size, multifocality, and growth of this tumor. Identification of this lesion is paramount due to its low-grade malignant potential. • While PEM involving the conjunctiva has been...

...Paul O. Phelps; J. Andrew Carlson; Dale R. Meyer The authors present a case of a gradually enlarging pigmented mass of the upper eyelid and anterior orbit that was discovered to be the graphite tip of a pencil surrounded by macrophages bearing graphite and fibrous tissue. A 25-year-old woman...

... with no reported ocular symptoms was found to have an incidental right orbital mass on imaging. Additional studies revealed multiple liver lesions, which were biopsied and found to be consistent with adenoid cystic carcinoma. She was then referred to the ophthalmology service, where ocular examination demonstrated...

...Hardeep Singh Mudhar; Murtuza Nuruddin; Soma Roy Purpose: To describe the clinical, radiological and histopathological features of a highly unusual primary orbital glioma. Procedures: A 6-year-old female presented with right-sided proptosis that revealed a well-defined intraconal mass on CT imaging...

...Hayyam Kiratli; İrem Koç; Berçin Tarlan Aims: To report a patient with unrecognized small macular melanoma, who gradually developed neovascular glaucoma that was treated with an Ahmed valve. We presume that tumor cells gained access to the orbit through this aqueous drainage device. Methods...

... as histopathological characteristics with Kimura disease (KD), but they have been considered to be two distinct entities based on their histological features. Orbital and adnexal involvement in ALHE is rare. The published literature is limited to few case reports featuring single cases. Methods: We report a series...

...Cesar M. Salinas-La Rosa Purpose of the Study: To describe the rare occurrence of a paraganglioma in the orbit and how to triage for genetic testing and assess the prognosis with succinate dehydrogenase subunit B (SDHB) immunohistochemical staining. Method: Case report. Procedures: A 47-year-old...

...Frederick A. Jakobiec; David J. Ramsey; Anna M. Stagner; David M. Wu; Michael K. Yoon Purpose/Background: To report a patient with orbital extension of a choroidal metastasis produced by a pulmonary adenocarcinoma which was diagnosed by biopsy of the extrascleral nodule. Methods: Clinical history...