... in 5 of 58 (8.6%) cases: 3 (18.8%) cases of SCC, 2 (7.4%) cases of CIS, and none of CIN and conjunctival squamous papilloma. Disease recurrence was noted in 6 of the 40 (20%) cases. All recurrent cases tested negative for p16 immunohistochemistry. The patient’s human immunodeficiency virus infection...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Periocular sebaceous carcinoma Histomorphological features Immunohistochemistry Preferentially expressed antigen...

... (PRAME) status is an independent prognostic UM biomarker and a potential target for immunotherapy in metastatic UM. PRAME expression status can be detected in tumors using reverse-transcription polymerase chain reaction (RT-PCR). More recently, immunohistochemistry (IHC) has been developed to detect...

...), ribonucleic acid sequencing (RNA-seq), fluorescence in situ hybridization (FISH), and immunohistochemistry. Results: Three out of 4 of the invasive melanomas showed gains in 11q13 (CCND1 locus) by aCGH. FISH demonstrated CCND1 gain in invasive melanoma and in conjunctival melanocytic intraepithelial lesions...

... ]. Immunohistochemistry requires a minimal amount of tumor tissue while allowing diagnostic confirmation. Although infrequent, UM misdiagnosis based on clinical and radiological findings may occur [ 30 ], and genetic testing such as GEP would provide a result even in cases that are not UM [ 31 ]. For these reasons, BAP1...

...) in UM; however, changes in pathologic reporting for ER in breast carcinoma prompted a re-examination of ER in UM, as it could represent a potential therapeutic target. Objective: To determine if UM tumors express ER by immunohistochemistry (IHC) using current methodology for breast cancer...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Conjunctiva Primary acquired melanosis Intraepithelial melanocytic neoplasia Dendritic melanocyte Nevus cell Nevomelanocyte Origin of nevocyte Immunohistochemistry MART-1 HMB-45...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Immunohistochemistry Glaucoma implant Foreign body granuloma Minimally invasive glaucoma surgery Polyimide material is described as having excellent in vivo biocompatibility...

... metastatic lobular breast carcinoma. The diagnosis of a primary signet ring carcinoma in the lacrimal gland cannot be made by immunohistochemistry alone, because of overlaps with primary eyelid and metastatic breast signet ring tumors. A thorough systemic work-up should be done to rule out a primary...

... choroidal melanoma following I-125 plaque brachytherapy managed with enucleation. Clinical characteristics included tumor dimensions, radiation dose, time to local recurrence, and clinical pattern of recurrence. Histopathology (hematoxylin and eosin and periodic acid – Schiff) and immunohistochemistry (Ki...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Uveal melanoma Histone deacetylases Sirtuins Immunohistochemistry...

.... Conjunctiva Pathology Immunohistochemistry Tumor Biopsy Fibroxanthoma • Atypical fibroxanthoma is an uncommon tumor of the ocular surface with pathology revealing a highly cellular lesion with pleomorphic spindle cells, giant cells, and increased mitoses. • We provide a novel case report...

.... The initial diagnosis was malignant melanoma of the choroid. We resected the tumor and studied it histopathologically. The tumor tissue was investigated by light microscopy including immunohistochemistry using antibodies against S-100, HMB-45, EMA, and AE-1. Electron microscopic examination was also performed...

... muscle actin and vimentin, leading to the diagnosis of mesectodermal leiomyoma of the ciliary body. Results: We review the literature to expand upon the clinical findings, diagnostic methods, and histopathologic and immunohistochemistry characteristics of mesectodermal leiomyoma. Conclusion: Leiomyoma...

... HER2 overexpression in RB tissue samples and discussed its potential clinical utility. Methods: HER2 overexpression was investigated using immunohistochemistry; the overexpression was evaluated with a score ranging from 0 to 3+ according to the membranous staining pattern in archival formalin-fixed...

.... Methods: We conducted a retrospective study of tumors involving the ocular surface and ocular adnexa from 6 XP patients. Histopathological evaluation and immunohistochemistry was performed using antibodies directed against the most common mutated proteins in XP (XPA, XPC, and XPD). Results: Patients...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Choroid Orbit Lung carcinoma Metastasis Immunohistochemistry Metastatic tumors to the eye far outnumber primary intraocular malignancies [ 1,2 ]. The most common...

... to in the content or advertisements. Choroidal metastasis Immunohistochemistry Metastasis Tumor Small-cell carcinoma Neuroendocrine carcinoma Choroidal hemangioma We describe a case of metastatic neuroendocrine carcinoma presenting as an isolated choroidal mass and initially misdiagnosed...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Adenoma of the nonpigmented ciliary epithelium Sclerouvectomy Immunohistochemistry...