Article PDF first page preview

First page of Pediatric Ocular Surface Squamous Neoplasia in the Absence of Known Risk Factors and Systemic Conditions: A Case Series

Purpose To describe a case series of ocular surface squamous neoplasia (OSSN) in the pediatric population in Nepal. Design Retrospective case series. Methods Descriptive case series at a single tertiary eye care center in Nepal where children with histopathologically-proven OSSN were identified and their disease was characterized. Results OSSN was observed in 16 eyes of 16 pediatric patients (6-18 years old) with no identifiable risk factors. All patients were seen at Tilganga Institute of Ophthalmology, Kathmandu, Nepal, between May 2018 and June 2022. All lesions were histopathologically proven as OSSN and characterized by type. 9 (56%) were conjunctival intraepithelial neoplasia (CIN) I, 5 (31%) were CIN II, 2 (13%) were CIN III. There were no cases of squamous cell carcinoma. None of the patients had xeroderma pigmentosum, HIV, or Hepatitis B or C. Conclusions This work reports a case series of pediatric OSSN in the absence of risk factors and systemic conditions. More than half of the patients had mild CIN. Though rare, this case series highlights the importance of considering OSSN in the differential diagnosis of pediatric ocular surface lesions, perhaps especially in this geographic location.

Journal Section:
Clinical Research
This content is only available via PDF.
S. Karger AG, Basel
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
2025
You do not currently have access to this content.