...Katharina Schultheis; Ralf-Dieter Hofheinz; Deniz Gencer; James A. Blunk; Justus Benrath Background: Quality of life (QoL) is frequently investigated as a secondary endpoint in clinical trials but is rarely evaluated in clinical practice. The present survey sought to assess the QoL of patients...

... bisphosphonate, ibandronate, has been shown to reduce the risk of skeletal events after oral or intravenous administration in controlled clinical trials in various malignancies, and to confer significant palliation of bone pain and improvements in health-related quality of life in patients with metastatic breast...

... whether there are differences in the quality of life (QoL) of colorectal cancer patients who were treated in certified versus noncertified centers. Patients and Methods: A total of 284 colorectal cancer patients participated in the study: 184 patients from certified colorectal cancer centers and 100...

... outcomes, such as quality of life (QoL) assessment, are becoming more important as endpoint in clinical trials and for decision making regarding new anticancer product approvals. Nevertheless, numerous obstacles exist regarding the implementation of QoL assessment in the daily practice of medical...

... Binay Kumar Shahb aBSN, University of Illinois at Chicago College of Nursing, Chicago, IL, bSt. Joseph Regional Medical Center, Lewiston, ID, USA Keywords Palliative care · Quality of life · Survival · Healthcare providers · Terminally ill As more advanced medical technologies are becoming avail­ able...

...) and waiting group (WG) (n = 28). The 10-week twice weekly exercise group program consisted of gymnastics, movement games, relaxation, walking, and jogging. Anxiety, depression, body image, and quality of life were measured using standardized questionnaires. Maximal oxygen uptake (VO 2 max/kg) was assessed...

... with stage IIa BC received 6 cycles of either CAP or CEF (cyclophosphamide/epirubicin/5-fluorouracil) after surgery. The primary endpoint was overall survival (OS). Quality of life (QOL), patient acceptance of chemotherapy, and safety were secondary endpoints. Results: A total of 71 women were enrolled...

... weeks). Hemotoxicity was mild and reversible without therapy. Conclusion: Systemic Re-186 HEDP therapy appears to be a useful compound for palliation of painful osseous metastases and improves quality of life for men with advanced disseminated prostate cancer for the last remaining months of their life...

... of therapy was patient’s trust in conventional medicine (71%). Comparing ‘users’ and ‘nonusers’ of unconventional therapies showed that users are significantly younger, better educated and with a bigger women/men-ration among them. The groups did not differ with regard to most of the quality of life...

... quality of life subsuming physical, psychological and social well-being. 12 5 2009 © 1997 S. Karger AG, Basel 1997 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form...

... were body weight, appetite, Karnofsky performance status and quality of life, all of which were serially evaluated in monthly intervals until death. Results: A beneficial effect of MPA was noted in terms of weight as well as quality of life (measured by the functional living index for cancer...

... completed the Multidimensional Fatigue Inventory (MFI-20), in addition to the Hospital Anxiety and Depression Scale (HADS), the Quality Of Life questionnaire EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer QLQ-C30), the subscale ‘social support’ of the Functional Assessment...

... hopes of removing most of the psychological stress from the patients and improving their quality of life. Patients and Methods: Within the framework of this study the quality of life of women with primary breast cancer was investigated in dependence on their age and the nature of the operation. 27 women...

... quality of life. Conclusion : The case reported suggests that such a therapy approach combining intra-arterial, direct perfusion with radiotherapy for the management of pronounced and irreversible manifestations of pleural mesothelioma (stage IV) is effective even from a palliative point of view. Thus we...

... of ‘FOM’ treatment combined with its very low toxicity makes this regimen attractive to be tested in a randomized trial versus current cisplatin- or anthracycline based combinations for advanced NSCLC, evaluating primarily quality of life and including a control arm with best supportive care. 8 5...

... quality of life is the primary aim in treating patients with metastatic breast cancer. Patients and Methods: 224 patients from 11 centers were randomized to treatment with 40 mg/m2 of Adriamycin or with 40 mg/m2 of epirubicin or with 12 mg/m2 of mitoxantrone each in combination with 600 mg/m2...

... recommended as standard treatment in patients with advanced colorectal carcinoma. Recently, phase II trials demonstrated higher response rates for 5-FU and IFN than those anticipated for 5-FU alone. The present investigation was therefore undertaken to compare efficacy, toxicity, and quality of life of IFN...

... to in the content or advertisements. Malignant glioma Radiotherapy Radiosensitizers Chemotherapy Prognostic factors Quality of life ÜBERSICHTSARBEITEN REVIEW ARTICLES O nkologie 1992;15:178-189 M. Bamberg C.F. Hess Abt. Slrahlentherapie an der Universitätsklinik Tübingen Radiation Therapy...

...E. Heidemann; J. Kaesberger; P. Herschbach; A. Sellschopp There is growing consensus that patient-based criteria for assessment of the quality of life should supplement the judgements of physicians. There is, however, no widely accepted instrument that fulfills all stipulations. We therefore...

... for better moral design and moral monitoring of trial procedures, a better translation of medical health status data into individual quality of life criteria, and strong support for trust-based cooperation between physician, research team and patient. Existing bioethical questionnaires and detailed...