... with metastatic disease (palliative) surgery may be indicated, too. (Chemo-) Embolization should to be considered for liver metastases causing severe local symptoms. Recently, biotherapy with somatostatins or interferon-α has revolutionized the treatment of metastatic neuroendocrine tumor disease...

...-IIa we suggest PUVA alone or in combination with retinoids as the first-line therapy. If there is disease progression, interferon-α or methotrexate shall be added. CTCL cases in stage lib can be treated with PUVA combined with interferon-α and soft X-ray radiation (6-8 ×200 cGy, 50 kV twice/week...

...I. Funke; E. Späth-Schwalbe; G. Stohlmann; O. Prümmer; H. Gallati; H. Schrezenmeier; F. Porzsolt Background: In advanced renal cell cancer (RCC) interleukin-2 (IL-2) and interferon-α (IFN-α) have shown modest clinical activity as single agents, substantial toxicity being associated with IL-2...

...H. Hausmaninger; B. Oentrich; K. Nachbaur; D. Niederwieser; R. Haidinger; C. Huber Im Rahmen einer Phase-2-Studie wird versucht, eine Ansprechrate von 60–80%, die bei Patienten mit metastasierenden gastrointestinalen Karzinomen mit der Kombination 5-Fluorouracil und Interferon-α erreicht wurde, zu...

...H. Ludwig; W. Scheithauer; I. Kührer; R. Kuzmits; G. Gisslinger; W. Linkesch; Ch. Zielinski; E. Fritz Natürliches Leukozyteninterferon und rekombinantes Interferon-α-2 bewirken beim multiplen Myelom Remissionsraten zwischen 10 und 20%, wobei nicht chemotherapeutisch vorbehandelte Patienten höhere...