... triplet chemotherapy regimens in this setting. We report the treatment outcome in 3 patients with HER2-positive metastatic gastric cancer who were treated with trastuzumab plus the triplet FLOT regimen (5-fluorouracil/leucovorin, oxaliplatin, and docetaxel). Patients and Methods: 3 patients with HER2...

...Efraim Idelevich; Hanoch Kashtan; Yoram Klein; Victor Buevich; Noa Ben Baruch; Michael Dinerman; Margarita Tokar; Yulia Kundel; Baruch Brenner Background: We investigated the efficacy and tolerability of cisplatin and 5-fluorouracil (5-FU) plus bevacizumab as neoadjuvant therapy for patients...

... to in the content or advertisements. Colorectal cancer Irinotecan 5-Fluorouracil Metastatic disease Age Combination therapy Original Article · Originalarbeit Onkologie 2010;33:684 690 DOI: 10.1159/000322208 Published online: November 22, 2010 Efficacy and Safety of Irinotecan-Based Chemotherapy...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Adjuvant chemotherapy 5-Fluorouracil Leucovorin Levamisole Colon cancer OHKOLOGIE Ongoing Clinical Trial Laufende...

... recurrence and distant metastatic disease as well as an increase in overall survival following adjuvant radio-chemotherapy in high-risk stages of rectal cancer. The NCI and European groups currently recommend local radiation and 6 months of adjuvant chemotherapy with 5-fluorouracil (5-FU) for TNM stage II...

.... Metastatic colorectal carcinoma Systemic chemotherapy High-dose therapy 5-Fluorouracil Folinic acid ONKOLOGIE O riginal Article Originalarbeit Onkologie 1997:20:222-225 M. Lorenz E. Staib-Sebler C. Gog H. Petrowsky A. Encke Klinik für Allgemeinchirurgie, Klinikum der Johann Wolfgang...

... with levamisole and 5-Fluorouracil (5-FU) in comparison to a group of patients who had undergone surgery only. The mortality rate was reduced by 33%. The study carried out by the Oncological Center of Stuttgart aimed to reproduce these results. Patients and Methods: Having had a curative resection of a colon...

... Rectal cancer Adjuvant chemotherapy Locoregional Chemotherapy 5-Fluorouracil Leucovorin Mitoxantrone © 1996 S. Karger AG, Basel 1996 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced...

...C. Stoffregen; K.-H. Zurborn; V. Boehme; A. Schmid; G. Lorenz; T. Arendt; U.R. Fölsch Background: Weekly high-dose 5-fluorouracil (5-FU; 24-hour infusion of 2.6 g/m 2 ) and folinic acid (FA; 500 mg/m2as 1- or 2-hour infusion) proved to be effective in patients with metastatic colorectal cancer...

... inoperable squamous cell carcinoma of the esophagus received on days 1-5 and days 29-33 a chemotherapy with 5-fluorouracil as a continuous infusion of 1,000 mg/m2 daily over 24 h and cisplatinum 20 mg/m2 as short infusion daily over 60 min, combined with a simultaneous radiotherapy using a total dose of 30...

...R.M. Mader; H. Rainer; G.G. Steger The saying ‘you can teach an old drug new tricks’ has been proven to be useful in the case of 5-fluorouracil (5-FU), when its ability to be modulated by non-cytotoxic drugs was discovered. This review summarises experimental preclinical and clinical data...

...R. Moser; H. Hausmaninger; H. Ludwig; M. Fridrik; H. Schmidt; B. Mlineritsch; M. Pecherstorfer; G. Michlmayr; Ch. Kopf; H. Samonigg Background : For treatment of advanced colorectal cancer sufficient data exist confirming the efficacy of biochemical modulation of 5-fluorouracil (5FU) by folinic...

... found. Following a postoperative chemotherapy with 5-fluorouracil (5-FU) and folinic acid (FA) (3 cycles) a significant regression of the metastases became evident. In absence of further distant metastases and local recurrence the potentially curative resection of the hepatic metastases was performed...

...N. Tsavaris; N. Mylonakis; Ch. Bacoyiannis; G. Papastratis; M. Katsikas; V. Papadimitrakopoulou; A. Macheras; A. Stamelou; P. Kosmidis Background : The combination of 5-fluorouracil (5-FU) and folinic acid (FA) has demonstrated activity in most gastrointestinal tumors. The addition of epirubicin...

...H. Wilke; P. Preusser; M. Stahl; H.J. Meyer; U. Fink; W. Achterrath; P. Busche; J. Meyer; A. Harstrick; H.-J. Schmoll; S. Seeber Background : Cisplatin is an active drug in advanced gastric cancer and acts synergis-tically with etoposide and 5-fluorouracil (5-FU). These were the reasons for adding...

...B. Steinke; E. Günther; W. Hirschmann; W. Sondern; K.H. Koniczeck; H.E. Wander; F. Natt; T. Wagner; H.F. Hinrichs; W. Roth Background: In most studies comparing 5-fluorouracil (5-FU) monotherapy versus the combination of folinic acid and 5-FU in the treatment of advanced colorectal cancer, a low...

...Ch. Schöber; H.-J. Schmoll The aim of this report is to define the characteristics of the cardiovascular syndrome associated with the use of 5-fluorouracil (5-FU) single-agent therapy based on a review of the literature. 38 patients were identified and evaluated according to their pretreatment...

...G. Hartung; P. Diezler; E. Hagmüller; W. Queißer In this review new approaches to adjuvant therapy of colon and rectum carcinomas are reported. Early trials in the 70s using 5-fluorouracil and other monotherapies did not show any advantage for prognosis. The use of combination chemotherapy (e.g. 5...

...B. Kau; M. Rieger; H. Sauer Aus experimentellen Untersuchungen geht hervor, daß Leucovorin (LCV) die ZytotoxizitÄt von 5-Fluorouracil (5-FU) deutlich zu modulieren vermag. Durch den kombinierten Einsatz beider Substanzen kommt es zu einer anhaltenderen und ausgeprÄgteren Hemmung der DNS-Synthese...

...D. Braumann; K. Mainzer; C. Günzl; B. Lewerenz Bei einem jungen, kardial gesunden Mann mit metastasierendem Pankreaskarzinom wurde eine 5-Fluorouracil (5-FU)-Dauerinfusion (25 mg/kg Körpergewicht/24 h über 5 Tage) durchgeführt. Im ersten Therapiezyklus traten nach ca. 56 h (im zweiten Zyklus nach...