Seit 1981 werden nicht-kleinzellige Bronchialkarzinome sowie Platten-epithelkarzinome aus dem HNO-Bereich im Rahmen einer Phase-II-Studie mit einer Polychemotherapie, bestehend aus Cisplatin, VP16 und Vindesin behandelt. Unter dieser Therapie beobachteten wir während des letzten Jahres bei 4 von 16 Patienten als unerwünschte Wirkung ein lokalisiertes transitorisches Ödem, welches bisher nicht beschrieben wird.

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