Bei 20 Patienten mit Karzinomen im Kopf-Hals-Bereich ist die Dunkeladaptation verzögert. Die Patienten haben gegenüber gesunden Kontrollen signifikant niedrigere Serum-Vitamin-A-Spiegel. Da ein Vitamin-A-Mangel erst nach längerer Zeit seines Bestehens zu einer Verzögerung der Dunkeladaptation führt, wird angenommen, daß das Defizit schon längere Zeit bestanden hat. Aufgrund der antineoplastischen Potenz des Vitamins könnte diesem Umstand eine Bedeutung bei der Entstehung und dem Wachstum der Tumoren zukommen. Die Ursache für den gestörten Vitamin-A-Stoffwechsel liegt möglicherweise in einer langdauernden Fehlemährung.

Keywords:
Vitamin-A-Mangel, Dunkeladaptation, Tumor
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© 1983 S. Karger AG, Basel
1983
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