Bei der Chemotherapie des metastasierten Mammakarzinoms wurde ein Plateau erreicht: Verschiedene Kombinationsbehandlungen führen zu equivalenten Remissionsquoten und vergleichbaren Überlebenszeiten, besitzen aber eine unterschiedliche Toxizität. Wir stellen unsere Ergebnisse vor, die wir mit einer Kombination von Vinblastin (6 mg/m2, 1 × pro Woche i.v.), 5-Fluorouracil (600 mg/m2, 1 × pro Woche i.v.) und Prednison (10–20 mg täglich per os) als Folgetherapie nach einer ineffektiven primären Chemotherapie erreichten und korrelieren die Ergebnisse zu prognostischen Faktoren und zur Vorbehandlung. Unsere Ergebnisse lassen den Schluß zu, daß durch verschiedene ZytostatikaKombinationen mit steigender Aggressivität mehrere Remissionen nacheinander erzielt werden können.

Keywords:
Mammakarzinom, Therapieversager, Chemotherapie
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© 1983 S. Karger AG, Basel
1983
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