Die Therapie mit offenen radioaktiven Stoffen bietet für die Klinik eine Reihe von Möglichkeiten, die der Onkologe und der Nuklearmediziner besser nutzen und verstärkt ausbauen sollten. Grundlagen, Indikationen und Ergebnisse der endolymphatischen Radionuklidtherapie, der selektiven Therapie mit Radiophosphor und Radiostrontium durch metabolische Anreicherung sowie der intraartikulären und endokavitären Therapie mit Radiokolloiden liegen vor. Eine intravenose Tumortherapie kann zur Zeit nicht empfohlen werden. Unsere Kenntnisse über die pharmakologische Beeinflussung des Stoffwechsels der therapeutisch verwendeten Radiopharmaka sind gering und unzureichend. Die zukünftige Radionuklidbehandlung benötigt wissenschaftliches Engagement und intensive Grundlagenforschung; der Aufwand erscheint jedoch bezüglich des zu erwartenden therapeutischen Gewinns gerechtfertigt.

Keywords:
Radionuklidtherapie, Extrathyreoidale Erkrankungen, Nuklearmedizinische Therapie
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© 1982 S. Karger AG, Basel
1982
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