25 Patienten mit kleinzelligem Bronchuskarzinom wurden in einem Zeitraum von 3 Jahren mit einer Kombination von Polychemo- und Radiotherapie behandelt. Als Polychemotherapie wurde Adriamycin, Cyclophosphamid und Vincristin (ACO) gegeben. Nach den ersten 3 Polychemotherapiestößen wurde der Tumor, der homolaterale Hilus und das Mediastinum bestrahlt, anschließend noch 2–3 Polychemotherapiestöße durchgeführt. Bei alien 25 Patienten konnte eine Remission erzielt werden. Die mittlere Remissionsdauer betrug bei lokoregional begrenzter Tumorausbreitung 12 Monate, bei Patienten mit disseminiertem Tumorbefall 8,6 Monate. Die mittlere Überlebenszeit betrug 14 Monate bzw. 10,9 Monate. Die Ergebnisse werden mit denen anderer Arbeitsgruppen verglichen und diskutiert.

Keywords:
Kleinzelliges Bronchuskarzinom, Polychemotherapie, Strahlentherapie
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© 1981 S. Karger AG, Basel
1981
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