Es wird der Verlauf eines Patienten mit multipler endokriner Neoplasie Typ II a Über sieben Jahre beschrieben. Trotz ausgedehnter diagnostischer Untersuchungen gelang es erst durch eine Knochenstanzbiopsie, die Metastasierung zu sichern. Alle therapeutischen Maßnahmen wie Kombinationschemotherapie, Sandostatin, Bromocriptin und 131Jod-Methylendiphosphonat-Therapie erwiesen sich als wenig wirksam in bezug auf Tumorreduktion oder VermÍnderung der Symptomatik.

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