...Mitsuaki Suzuki; Ichiro Aida; Isao Sekiguchi; Taro Tamada; Sumiaki Tsuru Effects of cisplatin and etoposide chemotherapy and/or continuous administration of oral anticancer agent UFT following the initial chemotherapy with cisplatin and etoposide on the tumor recurrence rate were studied...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fluoropyrimidine CCl 4 -induced liver dysfunction 5-Fluorouracil Tegafur [l-(2-tetrahydrofuryl)-5-fluorouracil] UFT...

.../II trial was performed to evaluate the efficacy and safety of continuous infusion of irinotecan combined with UFT plus leucovorin (LV) for metastatic colorectal cancer. Methods: Escalating doses of irinotecan (90–110 mg/m 2 ) were administered by 24-hour infusion on day 1. UFT 300 mg/m 2 /day and LV...

...Jaafar Bennouna; Mark Saunders; Jean-Yves Douillard 5-Fluorouracil (5-FU) has been the most widely used chemotherapeutic agent for metastatic colorectal cancer (mCRC) and 5-FU combination therapy improves efficacy compared with monotherapy. The oral fluoropyrimidine UFT (tegafur-uracil...

... in about 50% of patients during the 6-month FOLFOX4 regimen, and the frequent need for hospitalization, alternative regimens may be required. We aimed to determine whether a ‘maintenance’ therapy with oral UFT (uracil-tegafur) in patients responding to FOLFOX4 is able to maintain the response and improve...

...Gunnar Folprecht; Claus-Henning Köhne New drugs improved efficacy or convenience of treatment in metastatic colorectal cancer. The oral fluoropyrimidines capecitabine and UFT are less toxic but equally efficacious relative to intravenous bolus 5-fluorouracil (5-FU)/folinic acid (FA). These agents...

...Fujio Kasumi; Masataka Yoshimoto; Junichi Uchino; Rikiya Abe; Yasuo Nomura; Keizo Sugimachi; Hiroaki Nakazato; Osahiko Abe Meta-analysis of 5 studies on postoperative breast cancer cases (2 studies on surgery alone vs. tegafur plus uracil (UFT) and 3 studies on tamoxifen (TAM) alone vs. TAM + UFT...

...K. Nishimura; N. Nonomura; Y. Ono; M. Nozawa; T. Fukui; Y. Harada; T. Imazu; N. Takaha; H. Sugao; T. Miki; A. Okuyama Objective: To evaluate the clinical usefulness of an oral combination of cyclophosphamide, uracil plus tegafur (UFT) and estramustine in the treatment of patients with hormone...

... Colon cancer Fluoropyrimidines 5-FU UFT S-1 Xeloda ® (capecitabine) Emitefur Eniluracil Oral chemotherapy 5-FU has been studied in several different dosing regimens, including a daily bolus schedule for five consecutive days, weekly bolus schedules and continuous infusions extending...