... to in the content or advertisements. 2024 Chronic lymphocytic leukemia Pregnancy Pharmacological management Targeted therapy Chemotherapy Infection Chronic lymphocytic leukemia (CLL) is a hematologic malignancy that mostly affects adults over the age of 50, and more often men than women [ 1...

... validated the Lung-molGPA as described by Sperduto et al. [ 15 ] in large and independent cohorts [ 16-20 ]. Furthermore, there have been conflicting reports regarding the effect of gene alterations and targeted therapies on the clinical and biological features of metastatic brain tumors from NSCLC [ 21-25...

...Yasar Ahmed; Jose Javier Berenguer-Pina; Thamir Mahgoub Background: Lung cancer is the most common thoracic malignancy, representing the leading cause of cancer-related deaths worldwide with a 5-year survival rate of <10%. Summary: The emergence of targeted therapy and immunotherapy has changed...

.... The search strategy for MEDLINE (via PubMed) was as follows: [email protected] 15 07 2019 5 08 2019 2 10 2019 Cetuximab Pancreatic cancer Palliative cancer therapy Targeted therapy Survival Pancreatic ductal adenocarcinoma is one of the most...

.... Four of the 5 studies selected for this analysis have completed enrollment with final results published for 2 studies [ 26, 27 ]. Phase I study Targeted therapy Tolerability Toxicity Race Gender National Institutes of Health (NIH) 10.13039/100000002 Cancer...

... with ACC to targeted therapies. Methods: This is an analysis of 10 molecularly profiled ACCs that were progressing under standard of care treatment. The profile consisted of a 50-gene next-generation sequencing panel, immunohistochemistry (IHC), and fluorescence in situ hybridization for several proteins...

... and Google Scholar were searched for MUP patients treated with immunotherapy or targeted therapy reported in the literature, and their response and survival data were compared to the MUP patient data from NYU. Both groups' response data were compared to those reported for melanoma of known primary (MKP...

...- and MEK-targeted therapy and CTLA-4- and PD-1-blocking antibodies (immune checkpoint inhibitors, ICI). While novel therapies have demonstrated improved prognosis in clinical trials, few studies have examined the evolution of prognosis and toxicity of these drugs among an unselected population. We assess...

...: Pancreatic metastases (PM) from renal cell carcinoma (RCC) have been associated with long-term survival. The aim of this study was to evaluate the outcome of RCC patients with multiple glandular metastases (MGM) treated with targeted therapies (TTs). Methods: Sixty-four MGM patients treated between 1993...

... refused systemic chemotherapy and received targeted therapies with sunitinib (37.5 mg/day, 5 patients) or the mammalian target of rapamycin (mTOR) inhibitor everolimus (10 mg/day, 1 patient) as the first-line treatment. We evaluated the drugs' toxicities and survival. The median age of the patients was 55...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Targeted therapy Immunotherapy Clinical trials Anticancer drug activity Less than 3 percent of adult patients enroll in cancer clinical trials, and less than 50...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Precision cancer medicine Randomized clinical trials Novel study designs Targeted therapy It would...

... schedules [email protected] 28 7 2016 Cervix cancer Neo-adjuvant chemotherapy Adjuvant chemotherapy Concurrent chemoradiation Targeted therapy Bevacizumab Cervical cancer is a common malignancy among women in countries with limited resources. In India, its...

...Murtala B. Abubakar; Siew Hua Gan The advent of advanced molecular targeted therapy has resulted in improved prognoses for patients with advanced malignancies. However, despite the significant success and specificity of this advocated targeted therapy, significant on- and off-target adverse effects...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Next-generation sequencing Lymphoma PD1/PDL1 Targeted therapy EZH2 Risk stratification Recent advances in next-generation sequencing (NGS) have revealed the presence...

... Survival Targeted therapy Everolimus Breast cancer is the most common cancer in women. In menopausal women, breast cancers are mostly hormone-sensitive and require estrogen for growth and tumor proliferation. Hormonotherapy (HT), or endocrine therapy, is the reference treatment for metastatic...

... carcinoma and discuss methodological issues for drug investigation in this setting. Table 1 Progression-free survival in trials of the efficacy of targeted drugs for metastatic RCC (phase III) Fibroblast growth factor receptor 1 Renal cell carcinoma Targeted therapy Renal cell...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. targeted therapy Colorectal cancer Dear Editor, We read with great...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hepatocellular carcinoma Elderly patients Targeted therapy Sorafenib Hepatocellular carcinoma (HCC) is a major health problem worldwide...

..., the use of targeted therapies will likely be strongly controlled by health authorities. 31 05 2012 27 08 2012 16 10 2012 © 2012 S. Karger AG, Basel 2012 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other...