... of the polyenzyme preparation (as recommended for clinical use), PBMNC of healthy donors acquire the ability to produce TNF-α, IL-1β and IL-6 when incubated ex vivo with IFN-γ. Our results indicate that the biological effects observed after oral administration of polyenzyme preparations are realted to their ability...

...G. Hofmockel; I.D. Bassukas; D. Heimbach; R. Metz; M.P. Wirth The effect of recombinant human tumor necrosis factor alpha (TNF-α) on tumor growth and tumor cell proliferation of a human renal cell carcinoma transplanted into nude mice as well as on the body weight of the tumor-bearing animals has...