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1-19 of 19
Keywords: Solid tumors
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Journal Articles
Phase I Dose-Escalation and Pharmacokinetic Study of Intravenous Aflibercept in Combination with Docetaxel, Cisplatin, and 5-Fluorouracil in Patients with Advanced Solid Malignancies
Available to PurchaseRastislav Bahleda, Jackie Baker, Christophe Massard, Sirish M. Gadgeel, Jane E. Rogers, Hassan Izzedine, Eric Deutsch, Jeana L. Garris, Akbar Khan, Emmanuelle Boelle, Sylvie Assadourian, Jean-Charles Soria, Jaffer A. Ajani
Journal:
Oncology
Oncology (2016) 90 (1): 10–20.
Published Online: 23 October 2015
... aflibercept, a vascular endothelial growth factor decoy receptor protein (VEGF Trap), in combination with docetaxel, cisplatin, and 5-fluorouracil in patients with advanced solid tumors. Patients and Methods: Patients received 2, 4, or 6 mg/kg of intravenous aflibercept with docetaxel 75 mg/m 2 , cisplatin 75...
Journal Articles
TAS-106: Preclinical, Clinical and Beyond
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (2013) 85 (6): 356–363.
Published Online: 06 December 2013
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Antitumor ECyd RNA polymerase Solid tumors TAS-106 The great success of gemcitabine in combination with other...
Journal Articles
Escalating High-Dose Carboplatin and Autologous Bone Marrow Transplantation in Solid Tumors
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (1993) 50 (Suppl. 2): 47–52.
Published Online: 30 June 2009
.... Carboplatin Autologous bone marrow transplantation Solid tumors Cancer Oncology 1993;50(suppl 2):47-52 J.L. Pico3 A. Ibrahima L. Castagnaa / / / . Bourhisa A/. Chazarda D. Maraninchib 7.P. Droza Institut Gustave-Roussy, Department of Medicine, Villejuif; Institut Paoli-Calmette. Division of Hematology...
Journal Articles
Beta-2-Microglobulin as a Tumor Marker in Solid Malignancies
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (1988) 45 (3): 162–165.
Published Online: 25 June 2009
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. pVMicroglobulin Carcinoembryonic antigen Solid tumors Tumor marker Oncology 45: 162-165 (1988) < 1988 S. Karger AG...
Journal Articles
Serum Lysozyme Levels in Patients with Solid Tumors
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (1979) 36 (1): 15–18.
Published Online: 10 June 2009
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Macrophage activity Malignant melanoma Serum lysozyme Solid tumors Oncology 36: 15-18 (1979) Serum Lysozyme Levels in Patients with Solid...
Journal Articles
Cytosine Arabinoside (NSC 63878) Toxicity and Antitumor Activity in Human Solid Tumors
Available to PurchaseSubject Area:
Oncology
Hugh L. Davis, jr., Donald B. Rochlin, Arthur J. Weiss, William L. Wilson, Neil C. Andrews, Robert Madden, Nell Sedransk
Journal:
Oncology
Oncology (1974) 29 (3): 190–200.
Published Online: 09 June 2009
...Hugh L. Davis, jr.; Donald B. Rochlin; Arthur J. Weiss; William L. Wilson; Neil C. Andrews; Robert Madden; Nell Sedransk Cytosine arabinoside was administered to 449 patients with a variety of solid tumors. The phase I study included doses of 0.8–3.5 mg/kg × 10 days, and a small number received 5...
Journal Articles
Cancer Chemotherapy: II. Results of 603 Courses of Therapy in 400 Consecutive Patients, Followed for 18–52 Months
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (1973) 27 (2): 137–152.
Published Online: 05 June 2009
...G.J. Hill, II; R.R. Larsen; Elaine M. Sas; B.I. Cohen; T.J. Irish; Elisabeth Kandel; J. Kogler Results of chemotherapy are presented in detail for 603 courses of therapy with 30 drugs in 400 consecutive patients with 22 types of solid tumors. An overall response rate of 20% was observed. The length...
Journal Articles
Cancer Chemotherapy: I. Methods, Agents and Overall Results in 400 Patients
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (1972) 26 (2-3): 206–222.
Published Online: 05 June 2009
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Solid tumors Complications Cytotoxic drugs Hormones Clinical therapy Palliation Complete responses Experimental drugs 5 6 2009 Oncology 26: 206-222 (1972...
Journal Articles
Chemotherapy in Solid Tumors of Childhood
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (1972) 26 (2-3): 250–258.
Published Online: 05 June 2009
... in Solid Tumors of Childhood T. I. Lawhorn, H. H. Stone and J. D. Martin, jr. Joseph B. Whitehead Department of Surgery, Emory University School of Medicine, Atlanta, Ga. Abstract. Several malignant tumors are unique Key Words to infants and children. Earlier diagnosis, improved Chemotherapy surgical...
Journal Articles
A Dose Escalation Study of the Biweekly Administration of Paclitaxel, Oxaliplatin and Capecitabine in Patients with Advanced Solid Tumors
Available to PurchaseSubject Area:
Oncology
Zacharenia Saridaki, Vasiliki Bozionelou, Nikolaos Kentepozidis, Athanasios Kotsakis, Nikolaos Vardakis, Antonia Kalykaki, Ioannis Gioulbasanis, Athanasios Karampeazis, Lambros Vamvakas, Vassilis Georgoulias, Dimitris Mavroudis
Journal:
Oncology
Oncology (2007) 72 (1-2): 45–50.
Published Online: 12 November 2007
...) and the maximum-tolerated doses of the paclitaxel, oxaliplatin (LOHP) and capecitabine combination in patients with advanced solid tumors. Patients and Methods: Patients received escalating doses of paclitaxel (starting dose 100 mg/m 2 ) and LOHP (starting dose 40 mg/m 2 ) on days 1 and 15 and capecitabine...
Journal Articles
A Dose Escalation Study of Pegylated Liposomal Doxorubicin (Caelyx) in Combination with Capecitabine (Xeloda) in Patients with Refractory Solid Tumors
Available to PurchaseSubject Area:
Oncology
E. Maltezos, K. Amarantidis, M. Trichas, M. Vasiliadis, M. Toromanidou, E. Chatzaki, A. Karayiannakis, A. Tsaroucha, K. Romanidis, S. Kakolyris
Journal:
Oncology
Oncology (2006) 69 (6): 463–469.
Published Online: 10 February 2006
... tumors. A phase I study was conducted in order to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of their combination in patients with refractory solid tumors. Patients and Methods: Fifteen patients with histologically confirmed inoperable solid neoplasms were enrolled...
Journal Articles
Dose Escalation Study on Oxaliplatin and Capecitabine (Xeloda) in Patients with Advanced Solid Tumors
Available to PurchaseSubject Area:
Oncology
S. Kakolyris, J. Souglakos, C. Kouroussis, N. Androulakis, G. Samonis, N. Vardakis, K. Amarantidis, S. Agelaki, D. Mavroudis, N. Xenidis, V. Georgoulias
Journal:
Oncology
Oncology (2004) 66 (4): 253–259.
Published Online: 29 June 2004
...S. Kakolyris; J. Souglakos; C. Kouroussis; N. Androulakis; G. Samonis; N. Vardakis; K. Amarantidis; S. Agelaki; D. Mavroudis; N. Xenidis; V. Georgoulias Objectives: Capecitabine (CAP) and oxaliplatin (OX) have shown interesting activity in a wide range of solid tumors. A phase I study was conducted...
Journal Articles
Subject Area:
Oncology
A. Bamias, G. Aravantinos, C. Kalofonos, N. Timotheadou, V. Siafaka, I. Vlahou, D. Janinis, D. Pectasides, N. Pavlidis, G. Fountzilas
Journal:
Oncology
Oncology (2003) 64 (2): 102–110.
Published Online: 03 February 2003
... in patients with solid tumors receiving chemotherapy. We conducted a randomized, open label study to assess the efficacy of erythropoietin in preventing transfusions and significant anemia (hemoglobin <10 g/dl) in patients with solid tumors receiving platinum-based chemotherapy. Methods: One hundred forty...
Journal Articles
New Chemotherapeutic Agents: Update of Major Chemoradiation Trials in Solid Tumors
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (2002) 63 (Suppl. 2): 29–38.
Published Online: 13 December 2002
...Walter J. Curran The institution of combined modality therapy for unresected solid tumors has resulted in significant improvements in tumor control and survival benefit compared with radiotherapy (RT) alone. A number of chemotherapy agents that can enhance the effectiveness of RT, such as cisplatin...
Journal Articles
A Dose-Escalation Study of Oxaliplatin and Vinorelbine in Patients with Advanced Solid Tumors
Available to PurchaseSubject Area:
Oncology
S. Kakolyris, C. Kouroussis, M. Koukourakis, D. Mavroudis, K. Malas, N. Vardakis, V. Bozionelou, K. Kalbakis, V. Georgoulias
Journal:
Oncology
Oncology (2002) 63 (3): 213–218.
Published Online: 16 October 2002
...S. Kakolyris; C. Kouroussis; M. Koukourakis; D. Mavroudis; K. Malas; N. Vardakis; V. Bozionelou; K. Kalbakis; V. Georgoulias Objectives: Vinorelbine (V) and oxaliplatin (OX) have shown interesting activity in a wide range of solid tumors. A phase I study was conducted in order to determine...
Journal Articles
Phase I Study of Paclitaxel (Taxol) and Pegylated Liposomal Doxorubicin (Caelyx) Administered Every 2 Weeks in Patients with Advanced Solid Tumors
Available to PurchaseSubject Area:
Oncology
D. Mavroudis, Ch. Kouroussis, S. Kakolyris, S. Agelaki, K. Kalbakis, N. Androulakis, J. Souglakos, G. Samonis, V. Georgoulias
Journal:
Oncology
Oncology (2002) 62 (3): 216–222.
Published Online: 06 June 2002
... favorable pharmacokinetic and toxicity profile than the free drug. We conducted a phase I study to determine the maximum tolerated doses (MTD) and the dose limiting toxicities (DLT) of the combination administered every 2 weeks in patients with advanced solid tumors. Patients and Methods: Treatment...
Journal Articles
A Phase I Clinical Trial of Topotecan Given Every 2 Weeks in Patients with Refractory Solid Tumors
Available to PurchaseSubject Area:
Oncology
S. Kakolyris, Ch. Kouroussis, J. Souglakos, D. Mavroudis, S. Agelaki, K. Kalbakis, N. Androulakis, N. Vardakis, L. Vamvakas, V. Georgoulias
Journal:
Oncology
Oncology (2001) 61 (4): 265–270.
Published Online: 21 November 2001
...S. Kakolyris; Ch. Kouroussis; J. Souglakos; D. Mavroudis; S. Agelaki; K. Kalbakis; N. Androulakis; N. Vardakis; L. Vamvakas; V. Georgoulias Objectives: Topotecan, a potent inhibitor of the enzyme topoisomerase I, has shown an interesting activity against several types of solid tumors, most notably...
Journal Articles
Potential of Xeloda ® in Colorectal Cancer and Other Solid Tumors
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (1999) 57 (Suppl. 1): 27–32.
Published Online: 21 July 1999
... that is administered orally and has been rationally designed to generate 5-FU selectively within solid tumors. Theoretically, it has two major advantages, which should translate into an improved therapeutic index: firstly, enhanced drug concentration at the cancer site and therefore greater anti-tumor activity...
Journal Articles
Rational Design of New Tumoractivated TM Cytotoxic Agents
Available to PurchaseSubject Area:
Oncology
Journal:
Oncology
Oncology (1999) 57 (Suppl. 1): 9–15.
Published Online: 21 July 1999
..., instructions or products referred to in the content or advertisements. Xeloda ® (capecitabine) 5-Fluorouracil Fluoropyrimidines Solid tumors Tumor-selective activation Oral chemotherapy 5-Fluorouracil (5-FU) is one of the most frequently used cytotoxic agents for the treatment of solid...