... of patients with carcinosarcoma who receive second-line chemotherapy. Objective: To investigate the outcome and prognostic factors of patients who received second-line chemotherapy for gynecologic carcinosarcoma. Methods: We retrospectively investigated patients with ovarian or uterine carcinosarcoma, who...

...-to-lymphocyte ratio (NLR) has been proposed as an indicator of cancer-related inflammation. The aim of our study was to examine the prognostic value of the NLR for patients with advanced gastric cancer receiving second-line chemotherapy. Methods: The association of overall survival (OS) in second-line...

...Hirofumi Mukai; Yasuhiro Hagiwara; Kentaro Imi; Hirotsugu Isaka; Kenichi Watanabe; Yutaka Matsuyama; for the SELECT BC Study Group Objective: We assessed the impact of treatment preferences in second-line chemotherapy on breast cancer prognosis using the SELECT BC study. Methods: The SELECT BC...

... Scollo; Davide Adriano Santeufemia; Cosimo Sacco; Gaetano Facchini; Sandro Pignata Background and Aims: Ovarian clear cell carcinoma (CCC) has a poorer prognosis than other subtypes of ovarian cancer. In this study, we evaluated the responsiveness to second-line chemotherapy in recurrent ovarian CCC...

...Christoph Elsing; Christina Herrmann; Carla Verena Hannig; Wolfgang Stremmel; Dirk Jäger; Thomas Herrmann Background: The role of second-line chemotherapy in advanced gastric cancer is not yet fully established. Patients and Methods: We analysed 111 patients with advanced gastric cancer treated...

... ]. Overall, these data support the use of second-line chemotherapy in patients with MPA with good PS progressing after a frontline chemotherapy. These data should, however, be interpreted with caution because second-line chemotherapy was only evaluated in 1 phase III trial [ 19 ]. Unfortunately, this trial...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Gemcitabine Sarcoma Second-line chemotherapy Tolerability Treatment outcome Oncology Reducing the Worldwide Burden of Cancer Oncology 2010;78:5 11 DOI: 10.1159...

... the objective response rate and survival outcomes as second-line chemotherapy in patients with metastatic breast cancer who have failed a paclitaxel-containing regimen. Methods: Patients were randomized to receive either weekly docetaxel 40 mg/m 2 (group A, n = 34) or the combination of weekly docetaxel 35 mg/m...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Advanced lung cancer Comorbidities Combination chemotherapy Elderly cancer patients Non-small cell lung cancer Prognostic factor, response Second-line chemotherapy...

...Georgia Karpathiou; Evangelia Argiana; Anastassios Koutsopoulos; Marios E. Froudarakis We report the case of a 56-year-old patient with malignant pleural mesothelioma of epithelial type, who responded to second-line chemotherapy with lipoplatin plus gemcitabine. Diagnosis and staging of the disease...

...Christina Herrmann; Ulrich Abel; Wolfgang Stremmel; Dirk Jaeger; Thomas Herrmann Objectives: Second-line chemotherapy is widely used in advanced pancreatic cancer. However, only few data exist concerning the question who might benefit from second-line therapy. We intended to identify prognostic...

... chemotherapy and subsequently treated with one of the four following chemotherapy regimens: irinotecan, oxaliplatin and irinotecan or oxaliplatin both combined with the de Gramont schedule (LV5-FU2). Results: 225 patients (137 males and 88 females), were eligible for analysis. Second-line chemotherapy...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 5-Fluorouracil Methotrexate Folinic acid Second-line chemotherapy Metastatic colorectal cancer Phase 2 study...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Second-line chemotherapy in metastatic breast cancer is a matter of discussion, with two prevailing and opposing positions: some oncologists...

... treatment. Questions remaining to be addressed include the optimal starting dose of continuously infused 5-FU and whether the dose of folinic acid can be reduced or completely eliminated with respect to toxicity and health economics. Advanced colorectal carcinoma Second-line chemotherapy 5-Fluorouracil...