... to in the content or advertisements. 2025 Atezolizumab Bevacizumab Cachexia Hepatocellular carcinoma Prognosis Globally, hepatocellular carcinoma (HCC) ranks sixth among the most prevalent malignant cancers, but fourth in terms of cancer-related mortality [ 1 ]. In early-stage HCC, treatment...

... Mesothelioma Prognosis Survival Chemotherapy Latin America Pleural mesothelioma (PM) is a rare, yet highly aggressive cancer originating from the mesothelial lining of the pulmonary pleura, notorious for its poor prognosis. Although the precise global impact of mesothelioma remains uncertain...

..., and predicting the prognosis of lung cancer patients and using it to develop treatment strategies and interventions is important for prolonging the survival time of patients. Folate metabolism involves various aspects such as methylation of DNA, RNA, proteins, lipids, etc. Disorders of folate metabolism...

... of the poorest cancer prognosis rates; there is an urgent need to develop new drug therapies and biomarkers. CD63, a tetraspanin protein and well-known exosomal marker, is implicated in cancer progression; however, the significance of CD63 expression in ESCC remains unclear. Herein, we report the significance...

... to immunotherapy were analyzed by survival analysis, immune infiltration analysis, and immunotherapy response analysis. Results: We have developed a risk signature model based on eight key immune-related genes, which can classify patients into high-risk and low-risk groups. The prognosis of the high-risk group...

... of IRS-1 expression were associated with poor prognosis and increased lymph node metastasis. [email protected] 16 05 2024 13 08 2024 26 08 2024 Data extraction was carried out by two authors which included the author name, year of publication, the methodology adopted...

...Yu Liang; Yongmin Li; Rui Guo; Yan Zhao; Huanshuo Miao; Hong Chang; Yue Chen Introduction: Neuroendocrine differentiation is often found in colorectal cancer, but its impact on prognosis remains controversial. This study explored the association between neuroendocrine differentiation and prognosis...

...-/immunotherapy with an objective response rate (ORR) of 31.6% and a disease control rate of 57.9%. Median progression-free survival (PFS) and OS of PAED patients with systemic therapy were very poor (3.9 months and 5.9 months). Conclusions: Caucasian patients with TTF-1 negative PAED have a poor prognosis...

...: Immunohistochemistry (IHC) was utilized to assess SIA-IgG expression in tumor samples from 75 LSCC patients, aiming to investigate its correlation with clinical prognosis. In vitro functional experiments were conducted to explore the impact of SIA-IgG expression on the proliferative and migratory abilities...

..., further research is needed to explore the influence of USP52 on the prognosis of colorectal cancer (CRC), the tumor immune microenvironment, and therapeutic response. Methods: The differential expression of USP52 between CRC and normal tissues was analyzed using multiple public databases. The relationship...

... presented with frequent lesions and also with a more hazard ratio (2.7, 95% CI: 0.37–21) when analyzed by Kaplan-Meier survival analysis. Conclusion: CGH + SNP array changed the cytogenetic and IPSS-R risk group in 18% and 13% of patients, respectively, with an improved prediction of prognosis. This study...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Lung Adenocarcinoma SGLT2 Surgery Prognosis Lung...

... proportional hazards models and multivariable logistic regression were employed to identify independent risk factors of surgical site infection and prognosis. Results: Increased preoperative IBI significantly correlated with higher tumor stage. Patients with high IBI experienced shorter overall survival ( p...

... of the cuproptosis-related gene γ-glutamylcysteine synthetase (GCSH) on the prognosis of endometrial cancer (EC), the tumor immune microenvironment, and therapeutic response. Methods: The differential expression of GCSH between EC and normal tissues was analyzed using multiple public databases. Additionally, cancer...

... does not improve OS in patients with stage III breast cancer and has a worse prognosis. Preoperative RT has not changed the existing treatment paradigm in the current therapeutic context for patients with stage III breast cancer. [email protected] 28 02 2023 23 08 2023 25 09...

..., instructions or products referred to in the content or advertisements. 2023 Chemotherapy Metastatic colorectal cancer Prognosis Early-onset metastatic colorectal cancer Advancements in local and systemic therapies, coupled with the implementation of screening colonoscopies, have contributed...

...-BTCs patients. We identified MMR proficiency (pMMR)/deficiency (dMMR) according to the loss of MMR proteins (MLH1, PMS2, MSH2, MSH6). The primary objective of the study was to assess the incidence of dMMR in BTCs; the secondary purpose was to explore its association with prognosis and clinical features...

... a significant impact on the prognosis of patients with LGG only. In addition, in tumor microenvironment and tumor immune analysis, we found that the level of immune infiltration, tumor mutational load, microsatellite instability, and immune checkpoints of LGG were significantly correlated with SMG5 expression...

.... Consistent with published literature [ 9 ], our findings showed a poor prognosis for high circulating IL-8 levels in HCC patients, particularly in early-stage disease. © 2023 The Author(s). Published by S. Karger AG, Basel Open Access License / Drug Dosage / Disclaimer This article is licensed under...

... is a convenient and objective liver function evaluation index, which plays an important role in the prediction of patient survival rate and prognosis. Promoting the ALBI score in HCC can help doctors judge the patient’s condition and improve the diagnosis and precise treatment effect. Fig. 2. Cooperation...