... of the cuproptosis-related gene γ-glutamylcysteine synthetase (GCSH) on the prognosis of endometrial cancer (EC), the tumor immune microenvironment, and therapeutic response. Methods: The differential expression of GCSH between EC and normal tissues was analyzed using multiple public databases. Additionally, cancer...

... does not improve OS in patients with stage III breast cancer and has a worse prognosis. Preoperative RT has not changed the existing treatment paradigm in the current therapeutic context for patients with stage III breast cancer. liuhui2013_2018@163.com 28 02 2023 23 08 2023 25 09...

...-BTCs patients. We identified MMR proficiency (pMMR)/deficiency (dMMR) according to the loss of MMR proteins (MLH1, PMS2, MSH2, MSH6). The primary objective of the study was to assess the incidence of dMMR in BTCs; the secondary purpose was to explore its association with prognosis and clinical features...

..., instructions or products referred to in the content or advertisements. 2023 Chemotherapy Metastatic colorectal cancer Prognosis Early-onset metastatic colorectal cancer Advancements in local and systemic therapies, coupled with the implementation of screening colonoscopies, have contributed...

... a significant impact on the prognosis of patients with LGG only. In addition, in tumor microenvironment and tumor immune analysis, we found that the level of immune infiltration, tumor mutational load, microsatellite instability, and immune checkpoints of LGG were significantly correlated with SMG5 expression...

.... 2023 Interleukins Biomarker Hepatocellular carcinoma Overall survival Prognosis Hepatocellular carcinoma (HCC) is the most common liver cancer that usually develops in the setting of chronic liver inflammation and disease [ 1 ]. It is the third leading cause of cancer-related deaths...

... is a convenient and objective liver function evaluation index, which plays an important role in the prediction of patient survival rate and prognosis. Promoting the ALBI score in HCC can help doctors judge the patient’s condition and improve the diagnosis and precise treatment effect. 993368974@qq.com...

.... In this study, we aimed to evaluate the prognosis and the factors affecting the prognosis in brain metastatic patients with HER2-positive breast cancer. Methods: Clinical and pathological features of HER2-positive metastatic breast cancer patients and magnetic resonance imaging features at the onset of brain...

... Gastroesophageal adenocarcinoma Elderly Medically fit Survival Prognosis Surgery Chemoradiotherapy Gastroesophageal adenocarcinoma is an age-related disease and affects mainly older people as the incidence rates increase with age [ 1, 2 ]. As a result, the management of these cancers in the elderly...

... independent prognostic factors (all p < 0.05). Conclusion: Eligibility criteria determined by the SPIRITS trial may have clinical utility for predicting tumor response, the induction of conversion surgery, and prognosis in patients with advanced gastric cancer who underwent chemotherapy. arigami...

... complexes involved in nuclear import and are significant in tumor progression. Although high KPNA2 expression was associated with poor prognosis in solid tumors, the relationship between KPNA2 and KPNB1 expression and their prognostic role in gastric cancer (GC) remains unclear. Methods...

... with brain metastases (BM). Although BM have historically been associated with poor prognosis, it is unclear whether they remain a strong predictor of reduced survival. This study aimed to evaluate the prognostic value of BM and the utility of the Lung-molGPA. Methods: This single-center retrospective...

.... Metallothionein 2A MT2A Upper tract urothelial carcinoma Bladder cancer Prognosis Urothelial carcinoma (UC), which occurs in the mucosa of the urinary tract, is an important neoplasm of the urinary system that is usually noted in the urinary bladder [1]. In 2022, 81,180 new urinary bladder urothelial...

... nonampullary duodenal adenocarcinoma Microsatellite instability Prognosis Immunotherapy Small bowel adenocarcinoma (SBA) is rare compared with other gastrointestinal cancers, and primary small bowel malignancies are even rarer, accounting for less than 5% of all gastrointestinal tumors [1...

.... Palbociclib Progesterone receptor Ki67 Metastatic breast cancer Prognosis Table 1. Patients’ demographics and clinicopathological characteristics In addition, primary resistance to CDK4/6i is not uncommon and resistance has been reported to about 10% of the cases [2]. The mechanism...

... for downstaging in locally advanced lower rectal cancer. However, it remains unclear whether rectal cancers downstaged by preoperative therapy show similar prognoses to those of the same stage without preoperative therapy. We previously demonstrated that preoperative CRT did not affect prognosis of rectal cancer...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Systemic immune-inflammation index Non-small-cell lung cancer Trimodality therapy Prognosis Inflammatory state Lung cancer accounts...

.... Colorectal cancer Liver metastases Liver resection Prognosis Matrix metalloproteinase-8 Matrix metalloproteinase-9 Myeloperoxidase Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related death [1, 2]. Over half of the patients develop...

... interval [CI] 0.41–0.85; p = 0.005), high TLR5 expression (HR 0.60; 95% CI 0.45–0.83; p = 0.002), positive TLR7 expression (HR 0.49; 95% CI 0.33–0.72; p < 0.001), and low CRP (HR 1.48; 95% CI 1.08–2.11; p = 0.017) were associated with a better prognosis. A high TLR2 immunoexpression was associated...

... to in the content or advertisements. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Adjuvant chemotherapy Breast cancer Endocrine therapy Oncotype DX Recurrence Score Prognosis The Oncotype DX Recurrence Score...