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Keywords: Microsatellite instability
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Journal Articles
Journal Articles
Journal Articles
Subject Area:
Oncology
Journal: Oncology
Oncology (2020) 98 (8): 583–588.
Published Online: 10 June 2020
... pathway Microsatellite instability Gastric cancer (GC) is a highly aggressive type of cancer, and around half of the GC-related deaths occur in China [ 1 ]. Previous studies revealed that aggregation within families occurred in a sizable fraction (∼10%) of the GC patients [ 2 ]. The approval...
Journal Articles
Journal Articles
Subject Area:
Oncology
Journal: Oncology
Oncology (2016) 91 (5): 289–294.
Published Online: 28 September 2016
... in colorectal (CRC) and gastric (GC) cancers. Methods: There are mononucleotide repeats in EGR1 and BRSK1 , which could be mutated in cancers with defects in mismatch repair, resulting in microsatellite instability (MSI). We analyzed 124 CRCs and 79 GCs for mutations and their intratumoral heterogeneities (ITHs...
Journal Articles
Journal Articles
Subject Area:
Oncology
Journal: Oncology
Oncology (2016) 91 (3): 171–176.
Published Online: 12 July 2016
.... In blood samples obtained, we analyzed mutations in mismatch repair (MMR) genes, as well as protein expression by immunohistochemistry and microsatellite instability (MSI) in tumour tissue. Results: A total of 103 patients were enrolled. We detected 14 pathogenic mutations and 4 genetic variants of unknown...
Journal Articles
Journal Articles
Subject Area:
Oncology
Journal: Oncology
Oncology (2005) 68 (4-6): 548–557.
Published Online: 17 August 2005
... Cancer Institute Workshop on Microsatellite Instability (BAT25, BAT26, D5S346, D2S123, D17S250) were used in this study [ 19 ]. Products were run on an ABI 373A fluorescent DNA sequencer. PCR conditions are described elsewhere [ 9 ]. MSI was defined as the presence of an additional peak [ 9 ]. A tumor...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Oncology
Journal: Oncology
Oncology (1998) 55 (6): 569–574.
Published Online: 22 October 1998
...Masatoshi Watanabe; Taizo Shiraishi; Tsuyoshi Muneyuki; Moritaka Nagai; Kazuo Fukutome; Mariko Murata; Jyuichi Kawamura; Ryuichi Yatani A series of 25 primary prostate cancers in Japanese were screened for loss of heterozygosity and microsatellite instability using twelve microsatellite markers...