.... Cholangiocarcinoma Unresectable cholangiocarcinoma Intrahepatic cholangiocarcinoma Hepatic arterial infusion Floxuridine Intrahepatic chemotherapy Cholangiocarcinoma (CCA) arises from the biliary epithelium of intra- and extrahepatic bile ducts. The incidence of intrahepatic CCA has increased markedly...

...Utako Ishimoto; Shunsuke Kondo; Akihiro Ohba; Mitsuhito Sasaki; Yasunari Sakamoto; Chigusa Morizane; Hideki Ueno; Takuji Okusaka Objectives: Intrahepatic cholangiocarcinoma (ICC) is a rare type of liver cancer. No clinically useful prognostic factors have been reported for patients with advanced...

..., suppresses cell proliferation, and MOB1 liver conditional knockout mice develop intrahepatic cholangiocarcinoma (ICC). However, its clinical significance in human ICC has not been established. The aim of this study was to characterize protein levels and the role of Hippo and TGF pathways in ICCs. Methods...

... arterial infusion (HAI) with floxuridine (FUDR)/dexamethasone (Dex) in unresectable primary liver cancer. Methods: Patients with unresectable intrahepatic cholangiocarcinoma (ICC) or hepatocellular carcinoma (HCC) were treated with HAI FUDR/Dex plus IV Bev. Results were compared to a recent study of HAI...

.... Methods: GAGs from intrahepatic cholangiocarcinomas and differently differentiated hepatocellular carcinomas were extracted, purified and enzymatically digested. Their content, relative molecular size distribution and disaccharide composition were analyzed and compared using electrophoresis and high...

...Ryuji Ohta; Yo-ichi Yamashita; Akinobu Taketomi; Dai Kitagawa; Yosuke Kuroda; Shinji Itoh; Shin-ichi Aishima; Yoshihiko Maehara Objective: Focal adhesion kinase (FAK) expression has been linked to tumor cell invasion and metastasis, but its role in intrahepatic cholangiocarcinoma (ICC) has not been...