... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hepatocellular carcinoma Hepatoma Clinical trial Sorafenib Bevacizumab Erlotinib...

...Kayoko Nakamura; Atsushi Kubo; Saiko Hosokawa; Kazuhiro Nagaike; Shozo Hashimoto We studied the potential of alpha-interferon(IFN-Α) to enhance alpha-feto-protein (AFP) and thus alter the localization of 125 I-labeled antibody to the human hepatoma xenograft in athymic mice using monoclonal...

...C. Moroz; Z. Lantsberg; O. Sela; Y. Cohen; J. Khodadadi; J. Goldstein; M.R. Quastel; Y. Shoenfeld Two mouse monoclonal antiferritin antibodies were employed to detect tumors. In the first case a solitary hepatoma was defined, while in the second one, mediastinal metastases of breast cancer were...

...Geoffrey E. Packe; Clifford W. F. Clarke A patient with alcoholic liver cirrhosis, diabetes mellitus and porphyria cutanea tarda (PCT) is described, who subsequently died of hepatocellular carcinoma. The literature relating PCT to the incidence of primary hepatoma is reviewed, and the mechanisms...

...Stanley E. Order; Jerry L. Klein; Peter K. Leichner Radiolabeled antiferritin IgG will target ferritin-bearing tumors such as hepatoma, lung cancer, and neuroblastoma. In hepatoma 4 of 5 patients have had clinical remission of malignancy following intravenous doses up to 150 mCi of radiolabeled...

...Barry Grubbs; Waid Rogers; Ivan L. Cameron This study evaluates the effects of 13 days of total parenteral nutrition (TPN) on body weight, carcass mass and nitrogen balance in rats with and without a transplanted Morris No. 7777 hepatoma. Groups of rats without a tumor as well as rats with a tumor...

...Michael R. Felder; Wesley K. Church; Jaquelin B. Shaffer The activities and isozyme patterns of seven enzymes involved in glycolysis, the malate-aspartate shuttle and the pentose phosphate pathway have been examined in five transplantable murine hepatomas, adult liver and fetal liver. The liver...

...Ellas A.K. Alsabti Serum lipids were determined in patients with hepatoma, liver cirrhosis and healthy controls. Serum total cholesterol, esterified cholesterol, triglycerides, and phospholipid were increased in cases with hepatoma compared to those with cirrhosis, irrespective of a history...

...G.J. Mizejewski; M.R. Felder; L.T. Wimer; F. Ziegler Selected biochemical properties, based on hepatocellular function, were assessed in the mouse hepatoma BW7756 and host and/or normal mouse liver. These biochemical properties included (a) α-fetoprotein (AFP) production, (b) lipid composition, (c...

...B. Grubbs; W. Rogers; I. Cameron Rats bearing the Morris hepatoma No. 7777 were randomized into three treatment groups. Two of the groups received a nutritionally complete liquid formula diet per os ad libitum. One of these two groups received hydrazine sulfate (HS; an inhibitor of gluconeogenesis...

...Leopoldo J. Anghileri The role of the cellular lipoprotein in the metabolism of calcium and magnesium in Novikoff hepatoma ascites, liver of tumor-bearing, and liver of normal animals has been studied. The incorporation of 32 P indicates that in tumor cells the cellular lipoprotein present a much...

...J.K. Shuler; G.P. Tryfiates Cytoplasmic tyrosine aminotransferase (L-tyrosine: 2-oxoglutarate aminotransferase, EC2.6.1.5) was partially purified from host liver and Morris hepatoma No. 7777 grown in pyridoxine depleted rats. The animals were sacrificed six hours following the intraperitoneal...

...Leopoldo J. Anghileri The metabolism of acid mucopolysaccharides in Novikoff hepatoma and in hepatoma BW7756 was studied using the precursors 35S-sulfate, 3H-glucosamine and 14C-galactosamine. There is an active formation of sulfated mucopolysaccharides at the mitochondria and cell membrane level...

...G.P. Tryfiates The effect(s) of lack of dietary pyridoxine (PX) on the growth of Morris hepatoma no. 7288Ctc was studied. Buffalo strain female rats were fed a diet lacking PX. Pair-fed controls were fed the same diet with PX added. Animals were inoculated with no. 7288Ctc hepatoma cells at 21 days...

...J.R. Gilbertson; Rose A. Gelman; P. Ove; Mona L. Coetzee Intraperitoneal injection of trace amounts of corn oil prior to and following the injection of 40–50 mg of tissue from hepatoma 7777 or 7800 into the thigh of adult male Buffalo rats resulted in a marked decrease in the growth rate of both...

...N. Horiuchi; T. Kitamura; R. Tateishi; A. Wada A report is presented of a 57-year-old male with a giant mass in the left upper quadrant died of an alimentary tract bleeding. Autopsy revealed liver cirrhosis and hepatoma in the retroperitoneal space isolated from the liver. Oncology 27: 235-243...

... was found in 5 (1.1%) of the cancer patients, and in 3 (60%) of 5 patients with serum hepatitis. No Au Ag was found in any other sera tested. None of the 12 patients with hepatoma were found to have Au AG, while α-1-fetoprotein was found in the sera in 8 of the cases. © 1973 S. Karger AG, Basel 1973...

... conclude that a twice-weekly schedule of DIC should be further explored in the therapy of melanoma and other solid tumors. Chemotherapy Renal Carcinoma Bronchogenic Carcinoma Hepatoma Mesothelioma Esophageal Carcinoma Malignant Melanoma © 1971 S. Karger AG, Basel 1971 Copyright / Drug...

... inhibitor, trichostatin A (TSA), on hepatoma cells, however, has not been well studied. In this study, we examined cell viability and gene expression profile in hepatoma cell lines treated with TSA. Methods: To study cell growth inhibition and induction of apoptosis by TSA on human hepatoma cell lines...