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1-6 of 6
Keywords: Glioblastoma multiforme
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Journal Articles
Subject Area:
Oncology
Journal:
Oncology
Oncology (2019) 97 (5): 255–263.
Published Online: 09 July 2019
... was acceptable. Investigation of the NLR with larger groups of patients selected by MGMT status is warranted. Neutrophil/lymphocyte ratio Glioblastoma multiforme Combined modality Survival Glioblastoma multiforme (GBM), grade IV malignant glioma, is the most common primary brain tumor in adults...
Journal Articles
Subject Area:
Oncology
Journal:
Oncology
Oncology (2014) 88 (1): 28–48.
Published Online: 26 September 2014
...Jihong Zhang; Marc Hummersone; Charles S. Matthews; Malcolm F.G. Stevens; Tracey D. Bradshaw Glioblastoma multiforme (GBM) treatment includes temozolomide (TMZ) chemotherapy. O6-Methylguanine lesions are repaired by methylguanine-DNA methyltransferase (MGMT). Response to TMZ requires low MGMT...
Journal Articles
Subject Area:
Oncology
Pei-Ying Lee, Chi-Long Chen, Zhong-Zhe Lin, Ann-Lii Cheng, Edmund I-Tsuen Chen, Jacqueline Whang-Peng, Chi-Ying F. Huang
Journal:
Oncology
Oncology (2013) 84 (6): 326–335.
Published Online: 27 April 2013
...Pei-Ying Lee; Chi-Long Chen; Zhong-Zhe Lin; Ann-Lii Cheng; Edmund I-Tsuen Chen; Jacqueline Whang-Peng; Chi-Ying F. Huang Glioblastoma multiforme (GBM) is one of the most common and aggressive types of primary brain tumor. After complete surgical resection combined with radiation and chemotherapy...
Journal Articles
Subject Area:
Oncology
Jihong Zhang, Malcolm F.G. Stevens, Marc Hummersone, Srinivasan Madhusudan, Charles A. Laughton, Tracey D. Bradshaw
Journal:
Oncology
Oncology (2011) 80 (3-4): 195–207.
Published Online: 01 July 2011
... ). Glioblastoma multiforme Temozolomide O6-methylguanine-DNA methyltransferase Imidazotetrazines Anticancer activity Glioblastoma multiforme (GBM; grade IV astrocytoma) is the most prevalent and lethal primary malignant adult brain tumor [ 1,2 ]. Standard of care therapy comprises surgery...
Journal Articles
Subject Area:
Oncology
Journal:
Oncology
Oncology (2010) 78 (2): 103–114.
Published Online: 31 March 2010
...Jihong Zhang; Malcolm F.G. Stevens; Charles A. Laughton; Srinivasan Madhusudan; Tracey D. Bradshaw Treatment for glioblastoma multiforme includes the alkylating agent temozolomide combined with ionizing radiation. Persistent O6 -guanine methylation by temozolomide in O6 -methylguanine methyl...
Journal Articles
Subject Area:
Oncology
Ramon Martinez, Hans-K. Schackert, Jens Plaschke, Gustavo Baretton, Hella Appelt, Gabriele Schackert
Journal:
Oncology
Oncology (2004) 66 (5): 395–403.
Published Online: 02 September 2004
...Ramon Martinez; Hans-K. Schackert; Jens Plaschke; Gustavo Baretton; Hella Appelt; Gabriele Schackert Objective: Two chromosomal instability (CIN) pathways are described in glioblastoma multiforme (GBM), type 1 and type 2, which can be observed in up to 70% of the cases. Microsatellite instability...