... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Biliary tract cancer Cholangiocarcinoma Mismatch repair...

... cholangiocarcinoma has a poor prognosis and treatment options are limited. Combined systemic and intrahepatic chemotherapy may improve local control and enable downsizing. The aim of this study was to determine the maximum tolerated dose (MTD) of intravenous gemcitabine combined with intravenous cisplatin...

... and their potential anti-cancer activity. Data are not available in cholangiocarcinoma (CCA) patients. The aim of this study is to fill this gap by investigating the potential impact in terms of clinical outcome of the common non-cancer medications. Methods: All consecutive patients with CCAs were retrospectively...

...Chun Mei Yang; Jian Shu Background: Cholangiocarcinoma (CCA) is a relatively rare malignant biliary system tumor, and yet it represents the second most common primary hepatic neoplasm, following hepatocellular carcinoma. Regardless of the type, location, or etiology, the survival prognosis...

...Carlo Felix Maria Jung; Julie Lavole; Maximilien Barret; Einas Abou Ali; Lola-Jade Palmieri; Solene Dermine; Amélie Barré; Stanislas Chaussade; Romain Coriat Endoscopic decompression of bile duct stenosis in unresectable cholangiocarcinoma (CC) may be difficult due to localization of the tumor...

...Holger G. Hass; Ulrich Vogel; Michael Scheurlen; Jürgen Jobst Background: Due to late diagnosis and resistance to chemotherapy, most patients with cholangiocarcinoma have an unfavorable prognosis. Despite the use of immunohistochemistry (IHC) in clinical routine, differentiation between...

...) is a chronic cholestatic liver disorder characterized by multiple fibrotic strictures of the bile duct. More than 40% of deaths in PSC patients are related to malignant tumors, including cholangiocarcinoma. Primary hepatic adenosquamous carcinoma (ASC) is a rare subtype of cholangiocarcinoma containing...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cholangiocarcinoma Biliary tract...

...Utako Ishimoto; Shunsuke Kondo; Akihiro Ohba; Mitsuhito Sasaki; Yasunari Sakamoto; Chigusa Morizane; Hideki Ueno; Takuji Okusaka Objectives: Intrahepatic cholangiocarcinoma (ICC) is a rare type of liver cancer. No clinically useful prognostic factors have been reported for patients with advanced...

...François Chassagne; Teresa Rojas Rojas; Stéphane Bertani; Geneviève Bourdy; Sokha Eav; Eloy Ruiz; Pascal Pineau; Eric Deharo Objectives: Hepatocellular carcinoma (HCC) is the main type of primary liver cancer (PLC) worldwide, but cholangiocarcinoma (CCA) may be predominant in some specific regions...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Toxicity Tolerability Renal failure Cisplatin Cholangiocellular carcinoma Cholangiocarcinoma Biliary tract cancer...

...Wu-Chou Su; Kuo-Kuan Chan; Xi-Zhang Lin; Pin-Wen Lin; Nan-Haw Chow; Jeng-Shiann Shin; Chiung-Yu Chen; Chao-Jung Tsao A retrospective review of 130 patients with peripheral-type cholangiocarcinomas (PTCC), hilar-type cholangiocarcinomas (HTCC), extrahepatic cholan-giocarcinomas (EHCC), gallbladder...

...Yoshio Kinami; Yoshinao Ashida; Keitaro Seto; Shigeki Takashima; Ichiro Kita This study was performed to clarify the influence of incomplete bile duct obstruction (IBDO) on the occurrence of cholangiocarcinoma, using Syrian golden hamsters. These hamsters underwent simple laparotomy (SL) or IBDO...

...Yoshio Kinami; Yoshinao Ashida; Harukimi Gotoda; Keitaro Seto; Yasuhiko Kojima; Shigeki Takashima This study was performed to clarify the promoting effects of primary or secondary bile acid load on the occurrence of cholangiocarcinoma, using Syrian golden hamsters. These hamsters received...

...Tomohiro Iguchi; Natsumi Yamashita; Shinichi Aishima; Yousuke Kuroda; Takahiro Terashi; Keishi Sugimachi; Ken-ichi Taguchi; Akinobu Taketomi; Yoshihiko Maehara; Masazumi Tsuneyoshi Objective: Various immunohistochemical studies have been performed regarding intrahepatic cholangiocarcinoma (ICC...

... cholangiocarcinoma. The lesions regressed in response to chemotherapy, but they appeared again in connection with tumor relapse. Clinicians should recognize persistent erythema multiforme as one of the paraneoplastic dermatoses and efforts should be made to detect internal malignancies in patients with these skin...

...Bernard Paule; Marie-Olga Herelle; Estelle Rage; Michel Ducreux; René Adam; Catherine Guettier; Marie-Pierre Bralet Objectives: To assess the efficacy and safety of cetuximab in the palliative treatment of patients with intrahepatic cholangiocarcinomas (CCA) unresponsive to first-line gemcitabine...

...Matthew J. Olnes; Rodrigo Erlich Cholangiocarcinoma is a malignant neoplasm arising from the biliary epithelium that was first described by Durand-Fardel in 1840. Today, it continues to defy diagnosis and treatment. It is difficult to diagnose in part because of its relative rarity, and because...

...Yoshio Kinami; Minoru Miyakoshi; Kosaburo Fujikawa This study evaluated the influence of bile acid load on the DNA distribution pattern of proliferated bile ductules and cholangiocarcinoma induced by diisopropanolnitrosamine. Ninety hamsters were separated into control, tauro- and deoxycholic acid...