...Anne M.S. de Hoop; Karin Valkenet; Jaap J. Dronkers; Cyrille A.M. Krul; Jelle P. Ruurda; Cindy Veenhof; Raymond H.H. Pieters Introduction: Patients with cancer receiving radio- or chemotherapy undergo many immunological stressors. Chronic regular exercise has been shown to positively influence...

..., instructions or products referred to in the content or advertisements. 2023 Chemotherapy Metastatic colorectal cancer Prognosis Early-onset metastatic colorectal cancer Advancements in local and systemic therapies, coupled with the implementation of screening colonoscopies, have contributed...

... concentrations. Few studies have assessed the correlation between the GPS and the efficacy of chemotherapy in patients with extensive-stage small cell lung cancer (ES-SCLC). Therefore, this study aimed to evaluate the utility of the GPS in predicting the survival outcomes of patients with ES-SCLC. Methods...

...Naoki Fukuda; Ryosuke Oki; Hirotaka Suto; Xiaofei Wang; Tetsuya Urasaki; Yasuyoshi Sato; Kenji Nakano; Mayu Yunokawa; Makiko Ono; Junichi Tomomatsu; Hiroki Mitani; Shunji Takahashi Introduction: Although systemic therapy, including multi-kinase inhibitors and cytotoxic chemotherapy, is an option...

... Yasuda Introduction: Third-line chemotherapy has been suggested to improve survival in patients with gastric cancer. This study aimed to identify factors associated with the induction of third-line chemotherapy for advanced gastric cancer, focusing on patient eligibility for clinical trial. Methods: We...

... significance of eligibility criteria determined by phase 3 clinical trials in the clinical practice of patients with advanced gastric cancer who underwent chemotherapy. Methods: Patients with stage IV gastric cancer who received chemotherapy between February 2002 and December 2021 were retrospectively enrolled...

...; Hiroshi Miyata Background: Preoperative chemoradiation therapy (CRT) or chemotherapy (CT) followed by surgery is currently being administered for advanced esophageal cancer. However, few studies have directly compared CRT and CT for treating locally advanced esophageal carcinoma. This study aimed...

... Nakajima; Kazuhisa Takahashi Introduction: Cisplatin-based chemotherapy was established in the 1980s, and it has been improved by the development of a short hydration protocol in lung cancer therapy. However, cisplatin-based chemotherapy is still associated with renal toxicity. Because 5-aminolevulinic...

...Hee Jun Choi; Jun Ho Lee; Chang Shin Jung; Jeong Eon Lee; Youn Joo Jung; Seungju Lee; Seok-Kyung Kang; Hyun Yul Kim Introduction: Pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) is associated with improvement in survival outcomes. This study evaluated the pCR in patients...

... Introduction: Synovial sarcoma (SS) predominantly affects adolescents and young adults. Doxorubicin with or without ifosfamide therapy is the standard first-line treatment for unresectable or metastatic SS. However, there is no standard second-line chemotherapy regimen. The purpose of the current study...

...Hyera Kim; Ehyun Choi; Mi Hwa Heo; Jin Young Kim; Keon Uk Park Background: Elderly patients with extensive-disease small-cell lung cancer (ED-SCLC) have a high risk of chemotherapy toxicity due to multiple comorbidities and poor performance status. Although dose modification is often used to avoid...

... Background: The clinical benefit of systemic chemotherapy for recurrent/metastatic retroperitoneal/intra-abdominal soft tissue sarcoma (STS) compared to its benefits for other primary lesions has not been known or sufficiently evaluated. Methods and Patients: We retrospectively reviewed the cases of the STS...

... 1 (LAT-1) in clinical gastric cancer (GC) patients could predict patient therapeutic response to postoperative adjuvant chemotherapy. Methods: Immunohistochemistry was used to investigate LAT-1, CD98, and phosphorylated-mammalian target of rapamycin (p-mTOR) expression in 111 GC patients. To clarify...

...–0.93, p = 0.0162), and in patients who have started taking metformin after chemotherapy versus before chemotherapy and never users (HR 0.44, 95% CI 0.26–0.73, p = 0.0016). Conclusions: Our results highlighted that vitamin D intake improves DFS in patients undergoing surgery. Metformin intake after...

.... 2020 Endometrial cancer Medically unfit Hormonotherapy Chemotherapy Brachytherapy Hadrontherapy Endometrial cancer (EC) is the most common gynecological cancer in industrialized countries and second, after cervical cancer, in the developing world [ 1 ]. Most cases are in an apparent...

... strategies among international experts in peritoneal carcinosis, specifically their decision-making in the process of patient selection for hyperthermic intraperitoneal chemotherapy (HIPEC) in women suffering from ovarian cancer, to identify relevant decision-making criteria, and to quantify the level...

... of patients with carcinosarcoma who receive second-line chemotherapy. Objective: To investigate the outcome and prognostic factors of patients who received second-line chemotherapy for gynecologic carcinosarcoma. Methods: We retrospectively investigated patients with ovarian or uterine carcinosarcoma, who...

... enrolled 80 subjects with a histologically confirmed diagnosis of metastatic urothelial bladder carcinoma that had previously undergone chemotherapy with a platinum-containing regimen and had measurable lesions according to the Response Evaluation Criteria in Solid Tumors (RECIST). The patients ( n = 80...

... only distant metastases (29.5%), and 14 had both (31.8%). Patients with stage IVA CC experienced a radiotherapy with curative intent ( n = 14, 58.3%) +/– concomitant chemotherapy, or a palliative treatment ( n = 10, 41.7%). Twenty-three patients with stage IVB CC received a prior chemotherapy (52.3...

... chemotherapy plus vaginal brachytherapy (VBT). Methods: This investigation assessed 80 patients who underwent hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymphadenectomy for stage Ib-II, grade 2–3 endometrioid ( n = 43) or stage Ia-II nonendometrioid ( n = 37) endometrial cancer. Results: Five...