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Anne M.S. de Hoop, Karin Valkenet, Jaap J. Dronkers, Cyrille A.M. Krul, Jelle P. Ruurda, Cindy Veenhof, Raymond H.H. Pieters
Published Online: 04 October 2023
...Anne M.S. de Hoop; Karin Valkenet; Jaap J. Dronkers; Cyrille A.M. Krul; Jelle P. Ruurda; Cindy Veenhof; Raymond H.H. Pieters Introduction: Patients with cancer receiving radio- or chemotherapy undergo many immunological stressors. Chronic regular exercise has been shown to positively influence...
Bernhard Doleschal, Dora Niedersüß-Beke, Patrick Kirchweger, Andreas Petzer, Josef Thaler, Holger Rumpold
Published Online: 12 September 2023
..., instructions or products referred to in the content or advertisements. 2023 Chemotherapy Metastatic colorectal cancer Prognosis Early-onset metastatic colorectal cancer Advancements in local and systemic therapies, coupled with the implementation of screening colonoscopies, have contributed...
Satoshi Igawa, Hiroki Yamamoto, Kaori Yamada, Yuki Akazawa, Hiroya Manaka, Yuri Yagami, Yoshiro Nakahara, Takashi Sato, Hisashi Mitsufuji, Jiichiro Sasaki, Katsuhiko Naoki
Oncology (2023) 101 (11): 695–704.
Published Online: 26 July 2023
... concentrations. Few studies have assessed the correlation between the GPS and the efficacy of chemotherapy in patients with extensive-stage small cell lung cancer (ES-SCLC). Therefore, this study aimed to evaluate the utility of the GPS in predicting the survival outcomes of patients with ES-SCLC. Methods...
Naoki Fukuda, Ryosuke Oki, Hirotaka Suto, Xiaofei Wang, Tetsuya Urasaki, Yasuyoshi Sato, Kenji Nakano, Mayu Yunokawa, Makiko Ono, Junichi Tomomatsu, Hiroki Mitani, Shunji Takahashi
Oncology (2023) 101 (8): 502–511.
Published Online: 10 July 2023
...Naoki Fukuda; Ryosuke Oki; Hirotaka Suto; Xiaofei Wang; Tetsuya Urasaki; Yasuyoshi Sato; Kenji Nakano; Mayu Yunokawa; Makiko Ono; Junichi Tomomatsu; Hiroki Mitani; Shunji Takahashi Introduction: Although systemic therapy, including multi-kinase inhibitors and cytotoxic chemotherapy, is an option...
Takayuki Ando, Ayumu Hosokawa, Miho Sakumura, Iori Motoo, Shinya Kajiura, Katsuhisa Hirano, Takeshi Miwa, Tomotaka Yokota, Naokatsu Nakada, Yuko Ueda, Akira Ueda, Kenichiro Tsukada, Kohei Ogawa, Atsuko Nakaya, Akira Teramoto, Sohachi Nanjo, Hiroshi Mihara, Haruka Fujinami, Tsutomu Fujii, Ichiro Yasuda
Oncology (2023) 101 (1): 59–68.
Published Online: 24 January 2023
... Yasuda Introduction: Third-line chemotherapy has been suggested to improve survival in patients with gastric cancer. This study aimed to identify factors associated with the induction of third-line chemotherapy for advanced gastric cancer, focusing on patient eligibility for clinical trial. Methods: We...
Souichi Satake, Takaaki Arigami, Daisuke Matsushita, Keishi Okubo, Masataka Shimonosono, Ken Sasaki, Yusuke Tsuruda, Kan Tanabe, Shinichiro Mori, Shigehiro Yanagita, Yoshikazu Uenosono, Akihiro Nakajo, Hiroshi Kurahara, Takao Ohtsuka
Oncology (2023) 101 (1): 12–21.
Published Online: 24 January 2023
... significance of eligibility criteria determined by phase 3 clinical trials in the clinical practice of patients with advanced gastric cancer who underwent chemotherapy. Methods: Patients with stage IV gastric cancer who received chemotherapy between February 2002 and December 2021 were retrospectively enrolled...
Takahito Sugase, Keijiro Sugimura, Takashi Kanemura, Tomohira Takeoka, Masaaki Yamamoto, Naoki Shinno, Hisashi Hara, Takeshi Omori, Yoshiaki Fujii, Yosuke Mukai, Manabu Mikamori, Shinichiro Hasegawa, Naotsugu Haraguchi, Hirofumi Akita, Junichi Nishimura, Hiroshi Wada, Chu Matsuda, Masayoshi Yasui, Hiroshi Miyata
Oncology (2022) 100 (12): 655–665.
Published Online: 05 October 2022
...; Hiroshi Miyata Background: Preoperative chemoradiation therapy (CRT) or chemotherapy (CT) followed by surgery is currently being administered for advanced esophageal cancer. However, few studies have directly compared CRT and CT for treating locally advanced esophageal carcinoma. This study aimed...
Kodai Kawamura, Hidekazu Matsushima, Hiroshi Sakai, Akira Iwashima, Sukeyuki Nakamura, Tohru Kojima, Shinichi Sasaki, Takehiko Shigenaga, Ichiro Natsume, Takaaki Sasaki, Yoshinobu Ohsaki, Kentaro Iwanaga, Koichi Nishi, Yoichiro Mitsuishi, Hirokazu Taniguchi, Kazuhiro Sato, Mitsugu Yamauchi, Motowo Nakajima, Kazuhisa Takahashi
Oncology (2022) 100 (11): 620–632.
Published Online: 13 September 2022
... Nakajima; Kazuhisa Takahashi Introduction: Cisplatin-based chemotherapy was established in the 1980s, and it has been improved by the development of a short hydration protocol in lung cancer therapy. However, cisplatin-based chemotherapy is still associated with renal toxicity. Because 5-aminolevulinic...
Hee Jun Choi, Jun Ho Lee, Chang Shin Jung, Jeong Eon Lee, Youn Joo Jung, Seungju Lee, Seok-Kyung Kang, Hyun Yul Kim
Oncology (2022) 100 (10): 529–535.
Published Online: 26 July 2022
...Hee Jun Choi; Jun Ho Lee; Chang Shin Jung; Jeong Eon Lee; Youn Joo Jung; Seungju Lee; Seok-Kyung Kang; Hyun Yul Kim Introduction: Pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) is associated with improvement in survival outcomes. This study evaluated the pCR in patients...
Yuki Kojima, Tatsunori Shimoi, Takuji Seo, Shu Yazaki, Toshihiro Okuya, Yohei Ohtake, Hitomi S. Okuma, Akihiko Shimomura, Tadaaki Nishikawa, Maki Tanioka, Kazuki Sudo, Emi Noguchi, Kenji Tamura, Akihiko Yoshida, Shintaro Iwata, Eisuke Kobayashi, Akira Kawai, Yasuhiro Fujiwara, Kan Yonemori
Oncology (2022) 100 (7): 370–375.
Published Online: 11 April 2022
... Introduction: Synovial sarcoma (SS) predominantly affects adolescents and young adults. Doxorubicin with or without ifosfamide therapy is the standard first-line treatment for unresectable or metastatic SS. However, there is no standard second-line chemotherapy regimen. The purpose of the current study...
Oncology (2022) 100 (6): 313–319.
Published Online: 07 April 2022
...Hyera Kim; Ehyun Choi; Mi Hwa Heo; Jin Young Kim; Keon Uk Park Background: Elderly patients with extensive-disease small-cell lung cancer (ED-SCLC) have a high risk of chemotherapy toxicity due to multiple comorbidities and poor performance status. Although dose modification is often used to avoid...
Kenji Nakano, Naoki Fukuda, Yasuyoshi Sato, Tetsuya Urasaki, Akihiro Ohmoto, Xiaofei Wang, Naomi Hayashi, Hirotaka Suto, Shohei Udagawa, Ryosuke Oki, Mayu Yunokawa, Makiko Ono, Junichi Tomomatsu, Yusuke Minami, Keiko Hayakawa, Taisuke Tanizawa, Keisuke Ae, Seiichi Matsumoto, Shunji Takahashi
Oncology (2022) 100 (4): 238–246.
Published Online: 31 January 2022
... Background: The clinical benefit of systemic chemotherapy for recurrent/metastatic retroperitoneal/intra-abdominal soft tissue sarcoma (STS) compared to its benefits for other primary lesions has not been known or sufficiently evaluated. Methods and Patients: We retrospectively reviewed the cases of the STS...
Nobuhiro Nakazawa, Makoto Sohda, Munenori Ide, Yuki Shimoda, Yasunari Ubukata, Kengo Kuriyama, Keigo Hara, Akihiko Sano, Makoto Sakai, Takehiko Yokobori, Hiroomi Ogawa, Tetsunari Oyama, Ken Shirabe, Hiroshi Saeki
Oncology (2021) 99 (11): 732–739.
Published Online: 13 August 2021
... 1 (LAT-1) in clinical gastric cancer (GC) patients could predict patient therapeutic response to postoperative adjuvant chemotherapy. Methods: Immunohistochemistry was used to investigate LAT-1, CD98, and phosphorylated-mammalian target of rapamycin (p-mTOR) expression in 111 GC patients. To clarify...
Andrea Casadei-Gardini, Roberto Filippi, Margherita Rimini, Ilario Giovanni Rapposelli, Lorenzo Fornaro, Nicola Silvestris, Luca Aldrighetti, Giacomo Aimar, Giulia Rovesti, Giulia Bartolini, Caterina Vivaldi, Oronzo Brunetti, Elisa Sperti, Rosa La Face, Francesca Ratti, Kalliopi Andrikou, Martina Valgiusti, Laura Bernardini, Antonella Argentiero, Elisabetta Fenocchio, Giovanni Luca Frassineti, Silvia Cesario, Francesco Giovannelli, Virginia Quarà, Francesco Leone, Stefano Cascinu
Oncology (2021) 99 (5): 292–299.
Published Online: 24 February 2021
...–0.93, p = 0.0162), and in patients who have started taking metformin after chemotherapy versus before chemotherapy and never users (HR 0.44, 95% CI 0.26–0.73, p = 0.0016). Conclusions: Our results highlighted that vitamin D intake improves DFS in patients undergoing surgery. Metformin intake after...
Amelia Barcellini, Marianna Roccio, Concetta Laliscia, Francesca Zanellini, Diana Pettinato, Francesca Valvo, Alfredo Mirandola, Ester Orlandi, Angiolo Gadducci
Oncology (2021) 99 (2): 65–71.
Published Online: 09 February 2021
.... 2020 Endometrial cancer Medically unfit Hormonotherapy Chemotherapy Brachytherapy Hadrontherapy Endometrial cancer (EC) is the most common gynecological cancer in industrialized countries and second, after cervical cancer, in the developing world [ 1 ]. Most cases are in an apparent...
Thomas Steffen, Lukas Häller, Lana Bijelic, Markus Glatzer, Olivier Glehen, Diane Goéré, Ignace de Hingh, Yan Li, Brendan J. Moran, David L. Morris, Pompiliu Piso, Claudio A. Quadros, Beate Rau, Paul Sugarbaker, Yutaka Yonemura, Paul M. Putora
Oncology (2021) 99 (1): 41–48.
Published Online: 11 September 2020
... strategies among international experts in peritoneal carcinosis, specifically their decision-making in the process of patient selection for hyperthermic intraperitoneal chemotherapy (HIPEC) in women suffering from ovarian cancer, to identify relevant decision-making criteria, and to quantify the level...
Takahiro Ebata, Kan Yonemori, Tadaaki Nishikawa, Kazuki Sudo, Akihiko Shimomura, Emi Noguchi, Yasuhiro Fujiwara, Tomoyasu Kato, Kosei Hasegawa, Keiichi Fujiwara, Kenji Tamura
Oncology (2020) 98 (10): 699–705.
Published Online: 11 June 2020
... of patients with carcinosarcoma who receive second-line chemotherapy. Objective: To investigate the outcome and prognostic factors of patients who received second-line chemotherapy for gynecologic carcinosarcoma. Methods: We retrospectively investigated patients with ovarian or uterine carcinosarcoma, who...
Oncology (2019) 97 (6): 341–347.
Published Online: 28 August 2019
... enrolled 80 subjects with a histologically confirmed diagnosis of metastatic urothelial bladder carcinoma that had previously undergone chemotherapy with a platinum-containing regimen and had measurable lesions according to the Response Evaluation Criteria in Solid Tumors (RECIST). The patients ( n = 80...
Sophie Espenel, Max Adrien Garcia, Julien Langrand-Escure, Alexis Vallard, Jane Chloé Trone, Chloé Rancoule, Nicolas Vial, Pablo Moreno-Acosta, Céline Chauleur, Claire Boutet, Michel Peoc'h, Nathalie Prevot-Bitot, Jean Baptiste Guy, Nicolas Magné
Oncology (2019) 97 (3): 125–134.
Published Online: 02 July 2019
... only distant metastases (29.5%), and 14 had both (31.8%). Patients with stage IVA CC experienced a radiotherapy with curative intent ( n = 14, 58.3%) +/– concomitant chemotherapy, or a palliative treatment ( n = 10, 41.7%). Twenty-three patients with stage IVB CC received a prior chemotherapy (52.3...
Concetta Laliscia, Stefania Cosio, Riccardo Morganti, Valentina Mazzotti, Maria Grazia Fabrini, Fabiola Paiar, Angiolo Gadducci
Oncology (2019) 96 (5): 235–241.
Published Online: 22 March 2019
... chemotherapy plus vaginal brachytherapy (VBT). Methods: This investigation assessed 80 patients who underwent hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymphadenectomy for stage Ib-II, grade 2–3 endometrioid ( n = 43) or stage Ia-II nonendometrioid ( n = 37) endometrial cancer. Results: Five...