...Chung-Yen Huang; Yu-Chen Pai; Linda Chia-Hui Yu Background: Altered glucose metabolism is associated with chemoresistance in colorectal cancer (CRC). This study aimed to illustrate the molecular mechanisms of glucose-mediated chemoresistance against irinotecan, a topoisomerase I inhibitor, focusing...

... to in the content or advertisements. Adenoid cystic carcinoma Radioresistance Chemoresistance Hadrontherapy Vulvar cancer Rare gynecological tumors On the basis of the prevalence of cribriform or solid growing patterns, ACCs can be classified into three histological grades: Adenoid cystic...

..., there is an enrichment of cells with stem-like markers in relapsed tumors when compared with the primary tumor. This finding should be considered when developing treatment strategies. Chemoresistance Head and neck cancer Stem-like cells Table 1 Patient characteristics The following treatment...

... DNA methylation Colorectal cancer Prognostic factor Chemoresistance Colorectal cancer (CRC) is one of the leading causes of cancer-related death in the world [ 1 ]. Although CRC is generally recognized as a disease largely influenced by demographic factors and environmental exposure [ 2...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Ovarian cancer Radiation therapy Recurrence Chemoresistance In the USA, 21,550 people are diagnosed...

...Anne O’Meara; Atsushi Imamura; Pauline Johnson; Raymond Ball; Sean Rooney; Barry Kierce; Takashi Tsuruo; Peter Dervan P-Glycoprotein (P-gp), the product of the mdr-1 gene, is implicated in the development of chemoresistance in a variety of, mostly adult, cancers. Its role in paediatric tumours...

...–80%) and 4 (>80%). Retinoid receptor-alpha Retinoid receptor-beta Estrogen receptor-alpha Chemoresistance Prognostic factor Immunohistochemistry Western blot Serous ovarian cancer Several studies demonstrated the effect of retinoids in the chemoprevention of certain malignant...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Twist Immunohistochemistry Clear cell carcinoma, prognosis Chemoresistance Epithelial ovarian carcinoma...

... not appear to predict chemoresistance to the doxorubicin-containing regimen. Overexpression of p53 was seen in 22 patients, and surprisingly, was correlated with chemoresponse and a trend towards better survival. GSTπ expression was demonstrated in 13 cases (30%) and was not correlated with chemoresistance...

... to stimulate cell proliferation and to inhibit apoptosis in OSE and ovarian cancer cells. These data suggest that gonadotropins play an important role in the development, progression, and/or chemoresistance of ovarian carcinomas. Hormonal therapy against gonadotropins may be applicable for patients...