...Piyatida Molika; Rassanee Bissanum; Komwit Surachat; Kovit Pattanapanyasat; Jitti Hanprasertpong; Wilaiwan Chotigeat; Raphatphorn Navakanitworakul Introduction: Cervical cancer (CC) is the fourth most common cancer type and a leading cause of cancer-related deaths in women worldwide. Its underlying...

.... Among men in the AYA group, central nervous system (CNS) tumors accounted for 22.7% of all cancers, followed by germ cell tumors, 22.5%, and hematopoietic malignancies, 12.5%. Among women in the AYA group, cervical cancer accounted for 35.9% of all cancers, followed by breast cancer, 14.6%, and CNS...

... upregulation of cytokines such as IL-6 has been implicated in cervical cancer development and progression through several mechanisms, for example, by inducing platelet production, activation, and aggregation. The aim of the study was to evaluate the effective prognostic impact of inflammatory biomarkers...

... cervical cancer (deep stromal invasion [DSI], lymphovascular space invasion [LVSI], and bulky tumor) after radical hysterectomy. However, we previously reported that DSI, LVSI, and bulky squamous cell carcinoma (SCC) were not correlated with prognosis in multivariate analysis; therefore, the indications we...

... transvaginal ultrasound (3D TV-US) for evaluation of parametrial status in locally advanced cervical cancer patients after neoadjuvant chemotherapy (NACT), using histology as the gold standard. Methods: Consecutive patients with histologically confirmed cervical cancer were staged according to FIGO...

...Amelie de Gregorio; Peter Widschwendter; Florian Ebner; Thomas Wolfram Paul Friedl; Jens Huober; Wolfgang Janni; Nikolaus de Gregorio Objective: At the end of the year 2018, a new FIGO classification for cervical cancer was published, mainly revising stage IB and introducing a new stage IIIC, which...

... and compare prognostic factors, management strategies, and outcomes of very locally advanced cervical cancer (CC) (i.e., stage IVA) and metastatic CC (i.e., stage IVB). Method: A retrospective review was conducted based on all consecutive patients treated for stage IV CC in a comprehensive cancer care centre...

... of care for locally advanced cervical cancer (LACC). Pre-treatment lymph nodes (LN) assessment may have an important therapeutic role. CRT followed by adjuvant chemotherapy increased progression free survival (PFS) and overall survival (OS). Our study evaluated the feasibility and the effectiveness...

...Bogdan Obrzut; Andrzej Semczuk; Maciej Naróg; Marzanna Obrzut; Piotr Król Objective: We assessed the prognostic factors related to 10-year overall survival and disease-free survival in cervical cancer patients that underwent primary surgical protocols in 1 institution. Materials and Methods...

... with a significant rate of upstaging compared to clinical/radiological staging in patients with locally advanced cervical cancer. Objective: To analyze the stage-specific percentage of pelvic and para-aortic lymph node metastases and the upstaging ratio in a prospective randomized trial (Uterus-11). Methods: FIGO...

...Gauravi A. Mishra; Sharmila A. Pimple; Surendra S. Shastri Cervical cancer is the fourth most common cancer among women globally and the second most common cancer among Indian women. India alone bears 23% of the global cervical cancer burden. In India, population-based cervical cancer screening...

... and quality of life (QOL) in patients with locally advanced cervical cancer (LACC) treated with chemoradiation [chemotherapy/radiotherapy (CT/RT)] or neoadjuvant CT (NACT) followed by radical surgery (RS). Methods: Fifty-nine patients with LACC in remission after treatment with NACT + RS (n = 34) or CT/RT (n...

... (NACT) followed by radical surgery in patients affected by locally advanced cervical cancer. Methods: Patients affected by carcinoma of the uterine cervix FIGO (International Federation of Obstetrics and Gynecology) stage IB2-IIIB were enrolled into the study. The treatment schedule consisted of 5...

...-free survival (p = 0.036, p = 0.028, and p = 0.001, respectively). Conclusions: We profiled 32 genes that might be associated with prognosis in cervical cancer. We further revealed that the VIM gene is frequently methylated in cervical SCC and that its methylation might predict a favorable prognosis...

... and Methods: Between 2008 and 2012, 21 patients with primary cervical cancer stage FIGO I-II were enrolled in this prospective study. All women underwent nerve-sparing radical hysterectomy. Anorectal manometry was performed preoperatively and 6 months after surgery. A paired Student t test was used to assess...

...Pierluigi Benedetti Panici; Giorgia Perniola; Federica Tomao; Margherita Fischetti; Delia Savone; Violante Di Donato; Roberto Angioli; Ludovico Muzii Objective: It was the aim of this study to report on the role of laparoscopic staging in a large series of locally advanced cervical cancer (LACC...

...Masaharu Hata; Motoko Omura; Etsuko Miyagi; Izumi Koike; Reiko Numazaki; Mikiko Asai-Sato; Yoshibumi Tayama; Ichiro Ogino; Fumiki Hirahara; Tomio Inoue Objective: We carried out a review to determine the role of radiation therapy in uterine cervical cancer with distant metastasis. Methods: Forty...

...Daniela Baumann Cornelio; Luise Meurer; Gilberto Schwartsmann; Rafael Roesler Background: Cervical cancer is a leading cancer in women worldwide. The Papanicolaou test (Pap test) remains the main screening tool; however, it produces high rates of false-negative and false-positive results. Gastrin...

... activity of weekly bolus topotecan in the treatment of advanced or recurrent cervical cancer. Actually, there is no evidence to recommend this therapy in this patient population. 29 01 2011 7 06 2011 5 8 2011 © 2011 S. Karger AG, Basel 2011 Copyright / Drug Dosage / Disclaimer...

...Charles H. Evans; Anath A. Flugelman; Joseph A. DiPaolo Human papilloma viruses (HPV) are major factors in the etiology of cervical cancer. Natural killer (NK) lymphocytes, an important defense against viral diseases, are present in most HPV-associated lesions and cervical intraepithelial neoplasia...