...Shun Iwai; Nozomu Motono; Tsunehiro Oyama; Akihiro Shioya; Sohsuke Yamada; Hidetaka Uramoto Purpose: We aimed to elucidate the functions and clinical relevance of sodium-glucose cotransporter 2 (SGLT2) in resected lung adenocarcinoma. Methods: The protein expression of SGLT2 in tumor samples from...

...Mohan Hingorani; Rebecca Goody; Georgios Bozas; Khwaja Zahid; David James Mitton; Prashant Jain; Vincent Wong; Rajarshi Roy Background: Neoadjuvant chemotherapy (nCT) or chemoradiotherapy (nCRT) are accepted standards of care for the management of adenocarcinoma of the esophagus...

... 0.22; p < 0.001) were found to be independent prognostic factors. Conclusions: The number of NK cells in the largest diameter LNs can most likely be used as a predictor of recurrence. Colonic neoplasm Adenocarcinoma Natural killer cells Lymph nodes Survival analysis [email protected]...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chemotherapy Metastatic colorectal cancer Adenocarcinoma Regorafenib Quality of life The prognosis of patients with metastatic colorectal cancer (mCRC) is usually...

... Gillespie; Nabil F. Saba Objectives: Esophageal adenosquamous carcinoma (ASC) is a rare tumor with characteristics of adenocarcinoma (AC) and squamous cell carcinoma (SCC), the two most common esophageal cancers. Its behavior is aggressive but poorly understood. Using the National Cancer Database (NCDB...

..., instructions or products referred to in the content or advertisements. Metastatic castration-resistant prostate cancer Prednisone Adenocarcinoma Prostate neoplasm Chemotherapy regimen Taxanes Cabazitaxel In Western countries, prostate cancer is the second leading cause of death [ 1...

...%, respectively. The median age at diagnosis was 67.9 years (range 51.4-87.1). There were a total of 54 T1N0 tumors (92%) and 5 T2N0 lesions (8%). Adenocarcinoma was the most common pathology, comprising 54% of the lesions. A total of 16 of the patients (29%) failed. Among these, 5 local (9%), 14 regional (25...

...Alexios S. Strimpakos; Udai Banerji; Parames Thavasu; Alexandra Tsilimagou; Amanta Psyrri; Kostas N. Syrigos Background: The adenocarcinoma subtype of non-small cell lung cancer (adeno-NSCLC) is routinely treated with chemotherapy if patients do not have molecular aberrations such as epidermal...

... (range 20-91). Most of the patients were men (88.1%) and white (89.3%). The main primary site was the esophagogastric junction (84.9%) and the most frequent histology was adenocarcinoma (87.4%). The clinical characteristics of these patients are summarized in table 1 . The median follow-up time was 37.2...

... or not the expression of the EGFR-GEP100-Arf6 axis can be used as a biomarker for the prognosis of lung cancer has yet to be fully determined. Tumor specimens were collected from 182 patients who underwent a complete resection for lung adenocarcinoma. We analyzed phospho-EGFR (p-EGFR), GEP100, and Arf6 expression...

...) and overall survival were 9.0 (95% CI, 3.92-14.08) and 20.8 months (95% CI, 14.56-27.04), respectively. In multivariate analysis, adenocarcinoma (hazard ratio, HR, 12.25; 95% CI, 37.7-41.10; p < 0.001) and major mutations (deletions in exon 19 and L858R point mutation in exon 21; HR, 2.46; 95% CI, 1.14...

... . Among the matched population, male, adenocarcinoma, and Caucasian race dominated. At baseline, stage II was less common (DS group: n = 16, TMT group: n = 19) than stage III (DS group: n = 20, TMT group: n = 17). Table 1 Patient characteristics for prematched (left half) and matched (right half...

...Adriana Handra-Luca Objectives: The aim of this study was to determine the clinicopathological significance of blood group expression patterns in patients with surgically resected pancreatic ductal adenocarcinomas. Methods: Pancreatic ductal adenocarcinomas from 459 patients were analyzed...

... of adjuvant chemotherapy in patients with small bowel adenocarcinoma (SBA). Methods: Data from 52 patients with SBA who underwent curative surgery at the Asan Medical Center between January 1989 and December 2009 were retrospectively analyzed. Patients were divided into two groups: those who did (n = 23...

... survival (PFS) was 4.5/3.5/2.5/3.0 months, and overall survival (OS) was 8.0/8.5/7.8/6.5 months. Patients with adenocarcinoma had an improved PFS, but a similar OS. Never-smokers had longer PFS (7 months) and OS (13 months) than smokers and ex-smokers. Male patients had a slightly longer survival than...

... of the patients was 67 years (range from 42 to 88 years). The histology of the uterine neoplasms included 53 adenocarcinomas (59%), 19 sarcomas (21%), 12 adenosqamous carcinomas (13.5%), 4 adenoacanthomas (4.5%), and 2 clear cell adenocarcinomas (2%). Chest radiographs were retrospectively reviewed by two...

...Tetsuya Kusumoto; Yoshihisa Sakaguchi; Yoshihiko Maehara; Tadashi Nakashima; Motonosuke Furusawa; Keizo Sugimachi The chemosensitivities of squamous cell carcinoma (SCC) tissues from the head and neck area were compared to findings of adenocarcinoma, mainly from digestive organs. The sensitivity...

...Y. Becouarn; R. Brunet; E. Bussières; D. Marée Fifteen patients, median age 64 years, presenting with advanced gastrointestinal adenocarcinomas, were included in this study. The treatment combination consisted of folinic acid (200 mg/m 2 , IV bolus injection) followed by 5-fluorouracil (5-FU; 400...

...Hagop Kantarjian; Jaffer A. Ajani; David A. Karlin A phase II study of cis-diaminodichloroplatinum (II) (cis-DDP) was carried out in 55 patients with advanced adenocarcinoma of the upper gastrointestinal tract. The drug was given at a dose of 100 mg/m 2 i.v. over 2 h every 3–4 weeks, with hydration...

..., under these conditions, has been shown to be differentially inhibited by small numbers of cultured mouse and human cancer cells. We extend here these observations to co-cultures of retinal cells with small numbers (60:1 ratio) of human cells isolated from normal colon mucosa or colonic adenocarcinoma...