Background: Adenocarcinoma is the most frequent pathological type of stomach cancer. Hodgkin’s lymphoma is a lymphoproliferative disease arising from lymphoid tissue which is characterized by Reed-Sternberg cells. Synchronous occurrence of these two malignancies has not been reported in the English literature so far. Case: Here we present a 52-year-old male complaining of epigastric pain and fever diagnosed as stomach adenocarcinoma and Hodgkin’s lymphoma. Conclusion: It is thought that this case is the first of a synchronous stomach adenocarcinoma and Hodgkin’s lymphoma encountered in the English literature. It should be kept in mind that second malignancies can be seen in mass lesions in patients diagnosed with cancer.