... of forskolin in PC12 cells. This effect of NGF was well maintained even when NGF was removed after 4 days, even though the morphological features of neuronal differentiation were rapidly lost on removal of NGF. The enhanced cAMP production in response to forskolin could be due to a synergistic interaction...

...Shyi-Chyi Wang; Jiun-Tsai Lin; Yijuang Chern Adenosine 3′,5′-cyclic mononucleotide (cAMP) is one of the most important second messengers which govern cellular signal transductions. Adenylyl cyclases (ACs), which are cAMP-synthesizing enzymes, are responsible for cAMP production during extracellular...

...Roni Bash; Vardit Rubovitch; Mikhal Gafni; Yosef Sarne Cannabinoids are neurodepressive drugs that convey their cellular action through G i/o GTP-binding proteins which reduce cAMP formation and Ca 2+ influx. However, a growing body of evidence indicates that the stimulatory effects of cannabinoids...

... stimulation did not induce circadian expression of Per1. The effect of NE on Per1 level was dose- and receptor subtype-dependent, and both cAMP and cGMP induced Per1. Per1 was not induced by repeated NE – or forskolin – stimulation. Protein synthesis was not necessary for NE-induced Per1...

...A.V. Makarevich; A.V. Sirotkin The role of cAMP/protein kinase A (PKA)- and tyrosine kinase (TK)-dependent intracellular mechanisms in mediating the action of porcine growth hormone (GH) on insulin-like growth factor I (IGF-I) secretion by porcine ovarian granulosa cells was studied...

.... In contrast, a nuclear melatonin receptor agonist (1-[3-allyl-4-oxo-thiazolidine-2-ylidene]-4-methyl-thiosemi-carbazone, CGP52608) and 8-bromo-cAMP inhibited epididymal epithelial cell proliferation. Taken together, our data lead us to postulate that one of the possible physiological functions of melatonin...

.... Apoptosis Ovary Preantral follicle cGMP FSH cAMP KGF Biol Signals Recept 2000;9:81 86 The Regulation of Apoptosis in Preantral Ovarian Follicles Elizabeth A. McGee Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of Kentucky Chandler Medical Center...

... cAMP Growth factors Avian Biol Signals Recept 2000;9:96 101 Granulosa Cell Apoptosis: Conservation of Cell Signaling in an Avian Ovarian Model System A.L. Johnson Department of Biological Sciences, University of Notre Dame, Notre Dame, Ind., USA Key Words Ovary W Granulosa cell W Follicle atresia...

... rhythms with peaks at night. These rhythms appear to reflect circadian clock control of AA-NAT mRNA abundance and independent effects of light and darkness on both mRNA levels and enzyme activity. The effects of darkness and light may occur through alterations in cAMP-dependent protein phosphorylation...

... or receptors. Here we report the initial characterization of the signal transduction mechanisms by which indoleamines induce encystment of dinoflagellates. In particular, we explored the possible involvement of G proteins and cAMP in cyst formation. Both melatonin and 5-MOT promoted the encystment of Gonyaulax...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Parathyroid hormone receptors cAMP Fura-2 Inositol phosphates Phosphoinositide Calcium...

...Alexander V. Sirotkin; Jozef Nitray The secretion of oxytocin and arginine-vasopressin was demonstrated in bovine granulosa cell culture. It was found that dbcAMP or 3-isobutyl-l-methyl-xanthine (an inhibitor of intracellular cAMP metabolization) additions increased both oxytocin and vasopressin...

...Gang Yang; Zheng-Xiong Xi; Yu Wan; Hao Wang; Gang Bi Changes of angiotensin II and cAMP in plasma, brain tissue, adrenal gland and cardiovascular tissue during the acute and chronic stress were studied in rats. The acute stress group was subjected to compulsive cold water swimming for 20min, while...