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Keywords: Tumour necrosis factor
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Journal Articles

Tumour Necrosis Factor Induced an Early Release of Superoxide and a Late Mitochondrial Membrane Depolarization in L929 Cells : Increase in the Production of Superoxide Is Not Sufficient to Mimic the Action of TNF

Subject Area:
Neurology and Neuroscience
Samuel Ko, T.T. Kwok, K.P. Fung, Y.M. Choy, C.Y. Lee, S.K. Kong
Journal: Neurosignals
Biological Signals and Receptors (2001) 10 (5): 326–335.
https://doi.org/10.1159/000046900
Published Online: 07 August 2001
...Samuel Ko; T.T. Kwok; K.P. Fung; Y.M. Choy; C.Y. Lee; S.K. Kong Tumour necrosis factor α (TNF) cytotoxicity is mediated, at least in part, by oxidative stress. One of the post-receptor events shortly after the addition of TNF is the generation of the superoxide anion (O 2 – ·). In the present study...
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