... by neurotransmitters such as serotonin and dopamine. Fluctuations in beta-catenin in brain regions under duress have been associated with depressive-like behaviours. It is theorized that the change in behaviour can be attributed to the regulation of Dicer by beta-catenin. Dicer, a protein that produces micro-RNAs...

...John A. McNulty; M. Margaret Prechel Levels of vasotocin-like immunoreactivity (iVT) and the indoles serotonin (5HT), 5-hydroxyindole acetic acid, N-acetyl-serotonin (NAS) and melatonin were measured over 24-hour periods at monthly intervals in the pineal gland of male rats kept under constant...

... amino acids (γ-aminobutyric acid, GABA; taurine, glycine) and of somatostatin were measured in 2-month- and 18- to 20-month-old rats killed at six different time points along the 24-hour cycle. The striatal serotonin and dopamine turnover was also measured. Both young and middle-aged rats showed...

...David Pazo; Daniel P. Cardinali; Pilar Cano; Carlos A. Reyes Toso; Ana I. Esquifino The 24-hour rhythms of pineal norepinephrine (NE) content and serotonin (5-HT) turnover [estimated from the ratio of 5-hydroxyindoleacetic acid (5-HIAA) to 5-HT] were studied in young (2 months) and aged (18–20...

... significance of stimuli and is heavily interconnected with brainstem nuclei known to be involved in sleep control, has received little attention from sleep researchers. We report on a series of studies, focusing on its central nucleus (Ace). Presence of serotonin (5-HT) in Ace caused a rapid change of state...

...L. He; R.P. Tuckett; K.B. English An in vitro lateral thoracic skin preparation of the adult rat was used to test the effect of serotonin (5, 50, 500 μ M ) and control solutions on the response of the type I slowly adapting mechanoreceptor to a standard mechanical stimulus. Serotonin (5-HT...

... of incubation and harvested 3 and 6 h after UV exposure. It has been reported that the photosensitive enzymes N-acetyl transferase (NAT) and hydroxyindole- o -methyl transferase (HIOMT) are activated during the G 2 phase. The conversion of serotonin to melatonin is inhibited by UV exposure as seen at 3 h...

... (DA) and serotonin (5HT) turnover was examined in adult rats. In control rats, serum ACTH and prolactin exhibited peak values at the light-dark transition while the maximum in TSH was found in the late afternoon. GH levels did not vary on a 24-hour basis. In Freund’s-adjuvant-injected rats, 24-hour...

... or that pathways utilising transmitters other than EAA may be involved. When the non-specific serotonin agonist quipazine was administered at CTl 8, it mimicked both the acute and phase delaying effects of light on melatonin secretion and induced c-Fos in the SCN with a regional distribution identical...

...A. Ouarour; R.A. Cutrera; P. Pévet In the Djungarian hamster (Phodopus sungorus), using 5,7-dihydroxytryptamine (a specific neurotoxin), depletion of the serotonin (5-HT) fibers innervating the suprachiasmatic nuclei (SCN) was performed in animals displaying torpor bouts. The characteristics...

... the functional roles of 5-HT 1B and 5-HT 1D receptors. 5-HT 1B 5-HT 1D Receptors Serotonin 12 12 1994 © 1994 S. Karger AG, Basel 1994 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced...

...Toshihiko Iwanaga; Hongxia Han; Osamu Hoshi; Hiroaki Kanazawa; Isamu Adachi; Tsuneo Fujita Luminal stimulation of enterochromaffin (EC) cells is known to cause their release of serotonin which in turn may induce a variety of reflexes via mucosal intrinsic neurons. To morphologically support...

... stimulated melatonin (MEL), 5-methoxytryptophol (5-ML) and serotonin (5-HT) synthesis and release, whereas it did not affect pineal cyclic AMP levels. The stimulatory effect of DSIP on MEL secretion was dose dependent between 5 X 10 –6 and 10 –4 M, whereas the minimal effective concentration of DSIP on 5-ML...