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Keywords: Pregabalin
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Journal Articles
Subject Area:
Neurology and Neuroscience
Petra Hundehege, Juncal Fernandez-Orth, Pia Römer, Tobias Ruck, Thomas Müntefering, Susann Eichler, Manuela Cerina, Lisa Epping, Sarah Albrecht, Amélie F. Menke, Katharina Birkner, Kerstin Göbel, Thomas Budde, Frauke Zipp, Heinz Wiendl, Ali Gorji, Stefan Bittner, Sven G. Meuth
Journal:
Neurosignals
Neurosignals (2019) 26 (1): 77–93.
Published Online: 27 November 2018
...), but mostly fail in PMS. Pregabalin (Lyrica®) is prescribed to MS patients to treat neuropathic pain. Mechanistically, it targets voltage-dependent Ca 2+ channels and reduces harmful neuronal hyperexcitation in mouse epilepsy models. Studies suggest that GABA analogues like pregabalin exert neuroprotective...
Journal Articles
Subject Area:
Neurology and Neuroscience
Journal:
Neurosignals
Neurosignals (2011) 18 (4): 210–222.
Published Online: 30 December 2010
...D. Marmolino; M. Manto Background: Copper plays key roles in brain metabolism. Disorders of copper metabolism impact on neural signaling. The intracellular and extracellular concentrations of copper are tightly regulated. Pregabalin is a drug with multiple modes of action and has a high-affinity...