.... The elevation of reactive oxygen species generation in NFAT5 –/– neurons under H/I condition further confirmed that NFAT5 –/– neurons were more susceptible to oxidative stress. The present study demonstrated that activation of NFAT5 and its downstream SMIT induction is important in protecting neurons from...

... against hydrogen peroxide, β-amyloid protein (or peptide), glutamate, ischemia and staurosporine-induced cytotoxicity and apoptosis. These protective effects are related to its ability to attenuate oxidative stress, regulate the expression of apoptotic proteins Bcl-2, Bax, P53 and caspase-3, protect...

..., instructions or products referred to in the content or advertisements. Alzheimer’s disease Amyloid precursor protein Amyloid-β Neurofibrillary tangle Neuronal cell death Oxidative stress G protein c-Jun N-terminal kinase NADPH oxidase Humanin Neurosignals 2002;11:236 250 DOI: 10.1159...

... of catalase when expressed in the mitochondrial compartment is dependent upon the oxidant and the locus of ROS production. 24 5 2001 Mitochondria Catalase Hydrogen peroxide Oxidative stress Apoptosis © 2001 S. Karger AG, Basel 2001 Copyright / Drug Dosage / Disclaimer Copyright: All...

... protein which is severely reduced in FRDA patients. Loss of the homologue of frataxin in yeast is associated with mitochondrial iron overload, increased sensitivity to oxidative stress and profound deficit of oxidative phosphorylation. The demonstration that the human pathology of FRDA is also...

... Juan Jose Poderosob aInstitut National de la Santé et de la Recherche Médicale (INSERM) U408 and IFR 02, Faculté X. Bichat, Paris, France; bLaboratory of Oxygen Metabolism, University Hospital, University of Buenos Aires, Argentina Key Words Nitric oxide W Peroxynitrite W Oxidative stress W...

... of literature providing indirect support that oxidative stress occurs during exercise. The electron transport associated with the mitochondrial respiratory chain is considered the major process leading to ROS production at rest and during exercise. It is widely assumed that during exercise the increased...

... Oxidative stress Melatonin Oxygen metabolism Part I: Molecular Biology Invited Lectures Biol Signals Recept 1999;8:56 63 The Oxidant/Antioxidant Network: Role of Melatonin Russel J. Reiter Dun-Xian Tan Javier Cabrera Daniele D Arpa Rosa M. Sainz Juan Carlos Mayo Sofia Ramos Department of Cellular...

...Masayuki Hara; Masayuki Iigo; Ritsuko Ohtani-Kaneko; Naoko Nakamura; Takuro Suzuki; Russel J. Reiter; Kazuaki Hirata In an attempt to define the role of the pineal hormone melatonin and two analogues (5-methoxytryptamine, 5MT, and 6-hydroxymelatonin, 6HM) in limiting oxidative stress, the present...