... de Buenos Aires, Argentina Key Words Melatonin W Sleep disorders W Pineal gland W Circadian physiology W Melatonin receptors W Alzheimer disease Abstract Melatonin is synthesized and secreted during the dark period of the light-dark cycle. The rhythmic nocturnal melatonin secretion is directly...

...Mireille Masson-Pévet; François Gauer; Carole Schuster; Hilda Y. Guerrero We have investigated the photic regulation of melatonin receptors both at the level of binding capacity and mt 1 mRNA expression in the suprachiasmatic nucleus (SCN) and the pars tuberalis (PT) of the pituitary of two species...

... to in the content or advertisements. Melatonin receptors G protein Cations Brain Goldfish Radioreceptor assay 21 3 1997 BioloqicAl SiqNAls Original Paper Biol Signals 1997;6:29-39 Received: June 14, 1996 Accepted: November 16,1996 Masayuki ligoa Ritsuko Ohtani-Kaneko3 Masayuki Hara3 Atsuhiko...

...P.P.N. Lee; S.Y.W. Shiu; P.H. Chow; S.F. Pang Since melatonin and putative melatonin receptors can be detected in a variety of peripheral tissues, direct endocrine and paracrine actions of melatonin on the physiological functions of different organ systems in response to internal and external...

... no significant changes in the binding affinity. The reduction in 2[ 125 I]iodomelatonin binding may be a result of down-regulation of the melatonin receptors by elevated serum melatonin. Alternatively, it may be due to an indirect suppression of 2[ 125 I]iodomelatonin binding sites by the elevated sex hormones...

..., instructions or products referred to in the content or advertisements. Rainbow trout Coho salmon Arctic charr Atlantic salmon Iodomelatonin Pineal gland Brain tissue Diurnal rhythm Melatonin receptors Original Paper Biol Signals 1994;3:230-238 cs Pang- RK. Reddy- J.F. LealherlandGM. Browna S.F...

...G.M. Brown; C.S. Pang; S.F. Pang The existence of melatonin receptors in adrenal glands is suggested by effects on rodent adrenal function which follow pinealectomy or in vivo and in vitro melatonin treatment. In 1992, Persengiev and coworkers reported specific binding of 2-[ 125 I]iodomelatonin...

... of the binding characteristics by physiological variation in melatonin levels and/or immunological status of the animals provide evidence that these 2-[ 125 I]iodomelatonin binding sites in the lymphoid tissues may be physiologically significant and represent true melatonin receptors. The melatonin receptors...

...Mireille Masson-Pévet; François Gauer The density of high-affinity melatonin receptors in the pars tuberalis of different long day breeders exhibits a seasonal variation, with high values in spring-summer and low values in autumn-winter. In all the studies, this decrease in receptor density...

... to the pineal photoperiodic signal, melatonin, appropriately. Thus, we would like to hypothesize that melatonin receptors are present in the heart and lung. Using a specific labeled melatonin agonist, 2-[ 125 I]iodomelatonin, binding sites were demonstrated in the lung and heart of birds and other animals...

... blood flow, diminished epithelial sodium absorption, and inhibited the proliferation of jejunal epithelium. The use of a radiolabeled melatonin agonist, 2-[ 125 I]iodomelatonin, has allowed the study of putative melatonin receptors in the gut of duck, mouse, chicken and human. The gastrointestinal 2...

.... Melatonin Melatonin receptors Pineal gland Renal system Diurnal rhythm Hypertension Renin Urine output Cation Biol Signals 1993;2:207-220 Y. Songa E.A. Ayrea S.F. Pang3-b 3 Department of Physiology, Faculty of Medicine, University of Hong Kong; b Clarke Institute of Psychiatry, Toronto, Ont...

... binding sites in the whole brain, there were no significant differences (p > 0.05) between the two groups. The higher level of testicular 2-[ 125 I]iodomelatonin binding sites in photo-stimulated birds may be related to an up-regulation of melatonin receptors by the suppressed pineal melatonin...