...C.M. Clark; C. Davatzikos; A. Borthakur; A. Newberg; S. Leight; V.M.-Y. Lee; J.Q. Trojanowski The increasing prevalence of Alzheimer’s disease and the devastating consequences of late-life dementia motivates the drive to develop diagnostic biomarkers to reliably identify the pathology associated...

... of imaging and biochemical biomarkers. Biomarker tests that are shown to reliably predict the disease before it is clinically expressed would permit testing of new therapeutics at the earliest time point possible in order to give the best chance for delaying the onset of dementia in these patients...