.... Clinical presentation of GHB withdrawal can be life threatening. We aim, through this overview, to explore the neurobiological pathways causing GHB dependency and withdrawal, and their implications for treatment choices. Methods: In this work we review the literature discussing the findings from animal...

... in the published findings is undermined by the failure in previous studies to control for the effects of caffeine withdrawal and withdrawal reversal. Methods: Participants (n = 22) alternated weekly between ingesting placebo and caffeine (1.75 mg/kg) 3 times daily for 4 consecutive weeks. EEG activity was measured...

...N.E. Noldy; C.V. Santos; N. Politzer; R.D.G. Blair; P.L. Carlen Quantitative EEG changes were studied during cocaine withdrawal in 36 subjects. All subjects had used cocaine orally (n = 28) or intravenously (n = 8) within 48 h of admission to an inpatient unit. EEGs were recorded 2 and 6 days...

...N.E. Noldy; P.L. Carlen The effects of cocaine withdrawal on the latency of the P300 cognitive event-related potential were studied in 36 subjects. All subjects had used cocaine within 48 h of admission to an inpatient unit. P300 was recorded in a traditional auditory oddball paradigm 2 and 6 days...

..., instructions or products referred to in the content or advertisements. Anxiety Aversion Withdrawal Barbiturate Rat 20 2 2008 Neuropsychobiology 19: 86-89 (1988) © 1988 S. Karger AG, Basel 0302-282X/88/0192-0086$2.75/0 Evidence for Simultaneous Anxiolytic and Aversive Effects Several...

...Michael S. Eison Failure to gain weight during withdrawal from chronic regimens of dependence-producing drugs is observed in laboratory rats. Withdrawal from the benzodiazepine anxiolytic agent diazepam, whether induced by cessation of treatment or precipitated by administration of the specific...

...M. Saletu; B. Saletu; J. Grünberger; R. Mader; M. Karobath In a double-blind study the clinical symptomatology and quantitatively analyzed EEG of 42 hospitalized chronic alcoholics (ICD 303) undergoing alcohol withdrawal were investigated before, during and after 3 weeks’ treatment with 2...

...-induced hyperactivity may be due to the different dosages of amphetamine employed. 2 days after withdrawal from 3 weeks of chronic Li administration, rats showed no rebound supersensitivity of the hyperactivity response to 0.5 mg/kg d -amphetamine. Surprisingly, Li-withdrawn rats showed a marked...

... in the opposite environments. There were no differences found in locomotion between the CS+ and CS– environments following administration of HU-210. However, when the placebo was administered in the CS+ environment, there was a trend towards increased activity levels (p = 0.06), suggesting withdrawal-like...