... supporting this approach compared with antidepressant monotherapy, and almost no data comparing it with antidepressants of the latest generation, we conducted a retrospective chart analysis and a prospective, randomized open study on the efficacy and tolerability of nefazodone monotherapy versus combined...

... to in the content or advertisements. Depression Sleep Direct and indirect costs Treatment Antidepressants Tricyclic antidepressants Selective serotonin reuptake inhibitors Nefazodone Biological Psychiatry Main Editor: J. Mendlewicz (Brussels) Original Paper Neuropsychobiology 2000;42:107 119...

... improvement was observed. Reasons for this discrepancy will be discussed. Novel 5-HT reuptake inhibitors with additional modes of action such as 5-HT2 antagonism (e.g. trazodone, nefazodone) are more likely to improve objective and subjective sleep quality, although some shortcomings may be inherent in regard...