..., instructions or products referred to in the content or advertisements. Rostral anterior cingulate cortex Anterior insula Antidepressants Major depression Isolated effective coherence Pharmacotherapy with antidepressants is the standard protocol for treating patients with moderate to severe...

...Teresa Massardo; Juan C. Quintana; Luis Risco; Sebastian Corral; Jane Spuler; Daniel Vicentini; Gabriel Castro-Muñoz; Byron Riedel; Carolina Villa; Jaime I. Pereira Introduction: Major depressive disorder (MDD) is a prevalent condition which has a well-known association with ischemic cardiomyopathy...

... at awakening and the 24-h urine cortisol output, both measured at study baseline, with endpoint depression scores. Methods: Patients were admitted to a psychiatric inpatient ward with a major depressive episode and were started on fixed duloxetine treatment. They delivered saliva samples at awakening and 15...

...Alessandro Serretti; Diana De Ronchi; Paolo Olgiati Introduction: Irritable mood (IM) and subthreshold hypomanic symptoms are reported in half and two-fifths of major depressed subjects respectively, but their clinical and prognostic meanings remain unclear. The aim of this study was to test...

...Kathleen S. Bingham; Benoit H. Mulsant; Deirdre R. Dawson; Samprit Banerjee; Alastair J. Flint Introduction: Major depressive disorder (MDD) is associated with hypothalamic-pituitary-adrenal axis dysfunction that may persist into remission. Preliminary evidence suggests that this dysfunction may...

...Naohiro Takeuchi; Shinpei Nonen; Masaki Kato; Masataka Wakeno; Yoshiteru Takekita; Toshihiko Kinoshita; Fumihiko Kugawa Background: Antidepressants have variable therapeutic effects, depending on genetic and environmental factors. Approximately 30% of major depressive disorder (MDD) patients do...

...Thorsten Mikoteit; Ulrich Hemmeter; Anne Eckert; Serge Brand; Roland Bischof; Alexandra Delini-Stula; Edith Holsboer-Trachsler; Johannes Beck Background/Aims: In major depression cognitive impairment is common and may persist despite improvement in psychopathology. So far it is unclear how closely...

... treatment. The aim of the present study was to assess whether repeated testing of the cortisol awakening response (CAR) between baseline and after 10 days of duloxetine treatment is able to predict antidepressant treatment outcome after 6 weeks of treatment. Methods: 12 patients with a major depressive...

... with total HDRS or SHAPS scores (n = 10, Spearman's correlation test, all p > 0.19) were detected. [email protected] We enrolled 20 patients (10 males and 10 females, mean age: 48.05 ± 10.40 years) diagnosed with major depressive disorder according to DSM-IV-TR criteria [ 11 ]. Ten...

.... State-dependent gene expression variations have been described during a major depressive episode (MDE), in particular for SLC6A4 mRNA, but how this transcript varies in relation to MDE evolution remains unclear. In this study, we prospectively assessed time trends of SCL6A4 mRNA expression in responder...

...Brian H. Harvey; Mark Hamer; Roan Louw; Francois H. van der Westhuizen; Leoné Malan Background: Major depression is associated with evidence for metabolic and redox imbalance and also with reports of lower serum levels of brain-derived neurotrophic factor (BDNF). However, the relationship between...

...Bárbara Arias; Chiara Fabbri; Florence Gressier; Alessandro Serretti; Marina Mitjans; Cristóbal Gastó; Rosa Catalán; Diana De Ronchi; Lourdes Fañanás Background: Serotonergic genes have been widely investigated regarding antidepressant response in major depressive disorder (MDD) but results...

.... Cognitive function Repetitive transcranial magnetic stimulation Ultra-high-frequency stimulation Major depression Repetitive transcranial magnetic stimulation (rTMS) has transformed from a neurological research tool into a highly promising treatment alternative in psychiatry. Especially...

...Chi-Un Pae; Alberto Chiesa; Stefano Porcelli; Changsu Han; Ashwin A. Patkar; Soo-Jung Lee; Moon Ho Park; Alessandro Serretti; Diana De Ronchi Aim: The present study aimed to explore whether some single nucleotide polymorphisms (SNPs) within the BDNF gene could be associated with major depression...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Sleep deprivation Antidepressant Bipolar disorder Major depression...

... and long-term prognosis. We examined the effects of cerebrovascular changes on the course of geriatric depressive symptoms, dementia rates, and mortality over a follow-up period of approximately 10 years. Method: Participants were 84 patients with major depression (age of onset over 50 years); patients...

... predictors of outcome for these two different types of stimulation. Method: Seventy-four outpatients with a major depressive episode treated with an adequate antidepressant dosage for at least 4 weeks were included in our study and randomly assigned to two different groups: HFL or LFR rTMS. The Hamilton...

...). Results: Only 11 patients (48%) had a favorable follow-up, defined as absence of major depressive episodes during the observation period. Patients with a favorable and an unfavorable course did not differ in clinical or sociodemographic parameters, endocrinological results or continuation of lithium...

...Michael Kluge; Petra Schüssler; Dagmar Schmid; Manfred Uhr; Sara Kleyer; Alexander Yassouridis; Axel Steiger Background: In patients with major depression, the function of most endocrine axes is altered compared to healthy subjects. The orexigenic hormone ghrelin, which shows higher plasma levels...

..., instructions or products referred to in the content or advertisements. 2009 Physical activity Major depression Alzheimer’s disease Parkinson’s disease, elderly Review Neuropsychobiology 2009;59:191 198 DOI: 10.1159/000223730 Received: October 6, 2008 Accepted after revision...