... of the POMC (pro- opiomelanocortin) and NR3C1 (glucocorticoid receptor 1) genes. Twenty-eight heroin-dependent patients on DAM-assisted treatment received either DAM or saline in a randomized crossover design and 17 healthy participants received saline only. EDTA blood samples were taken 25 min before and 10...

... with heroin dependency were enrolled. Plasma oxytocin was measured using an ELISA kit. Novelty seeking was measured using an established instrument (the novelty seeking subscale of the Tridimensional Personality Questionnaire). Results: A significant negative association (ρ = -0.27, p = 0.02; r = -0.34, p...

...G. Gerra; R. Caccavari; B. Fontanesi; R. Delsignore; G. Fertonani-Affini; A. Marcato; D. Maestri; P. Avanzini; G. Perna; F. Brambilla Growth hormone (GH) and β-endorphin (β-EP) responses to clonidine stimulation were examined in 18 male heroin addicts, 9 with and 9 without previous histories...

...F. Brambilla; A. Guerrini; A. Guastalla; P. Beretta; D. De Maio The insulinemic and glycemic response to a glucose load (100 g per os) was studied in 21 heroin addicts, 16 males and 5 females, age 16–28 years, history of addiction lasting from 6 months to 4 years with heroin alone (from 0.5 to 1.5...

...Laura Costa; Lance O. Bauer Smooth pursuit eye movements were evaluated in 21 healthy volunteers and 126 patients meeting criteria for one of the following DSM-III-R dependence diagnoses: alcohol (n = 10), cocaine (n = 44), heroin (n = 34), or dual alcohol and cocaine (n = 38). A significant...