...Lijun Cui; Jingjing Lu; Zhongxia Shen; Jielin Zhu; Huanxin Chen; Shenliang Yang; Shikai Wang; Xinhua Shen Introduction: The etiology of generalized anxiety disorder (GAD) has not been fully understood, and oxidative stress may potentially contribute to its pathogenesis. However...

...Jingjing Lu; Weiwei Liang; Lijun Cui; Shaoqi Mou; Xuedan Pei; Xinhua Shen; Zhongxia Shen; Ping Shen Introduction: Activation of the inflammatory response system is involved in the pathogenesis of generalized anxiety disorder (GAD). The purpose of this study was to identify and characterize...

... to evaluate the efficacy of simvastatin augmentation versus placebo in the treatment of patients with generalized anxiety disorder (GAD) with residual symptoms despite treatment with selective serotonin reuptake inhibitors (SSRIs). Methods: A double-blind, 8-week controlled trial was conducted from August...

... of the anterior cingulate cortex (ACC) in adolescents with generalized anxiety disorder (GAD). Methods: Adolescents with GAD (n = 10) and healthy subjects (n = 10) underwent a 1 H MRS scan at 4 T. Glutamate (Glu), N-acetyl aspartate, creatine (Cr) and myo -inositol concentrations were measured in the ACC and were...

..., Remy von Frenckell, Georges Franck Psychiatric Unit. Centre Hospitalier Universitaire de Liège. Domaine Universitaire du San Tilman (B35), Liège, Belgium Key Words. Buspirone Oxazepam Generalized anxiety disorder Benzodiazepine Anxiolytic Benzodiazepine withdrawal Abstract. The anxiolytic...

...C. Wurthmann; E. Klieser; E. Lehmann; J. Krauth In the pharmacotherapy of chronic generalized anxiety disorder (GAD) rationally grounded guidelines on the treatment to choose in individual cases are not evident in the literature. The present study was designed to address this question in 30...

...Michael J. Garvey; Russell Noyes; Catherine Woodman; Cindy Laukes Twenty-one medication-free patients with generalized anxiety disorder (GAD) collected urine samples for 5-hydroxyindoleacetic acid (5-HIAA) and N-acetyl-β-glucosaminidase (NAG). Nine patients with no comorbid psychiatric diagnosis...

... in turn may cause – as a consequence of sleep pressure not slept off -diurnal tiredness. Neuropsvchobiology Pharmacopsychiatry Main Editor: B. Saletu (Vienna) Special Topic Section Neuropsychobiology of Generalized Anxiety Disorder and Its Pharmacotherapy Neuropsvchobiology 1997:36:117-129 Gerda Saletu...

... insomnia related to mild generalized anxiety disorder (GAD), as compared with LOR alone. After a placebo run-in phase of 1 week, they received active treatment (1 tablet SOM or LOR 1 mg) for 4 weeks and thereafter placebo again for 1 week. Clinical evaluations included the physician’s general assessment...

... metabolite vanillylmandelic acid (VMA) were measured in 46 patients with generalized anxiety disorder. There was a significant association between urinary levels of 5-HIAA and VMA: r = 0.79; p = 0.0001. Possible implications of this finding are discussed. 26 2 2008 © 1995 S. Karger AG, Basel...

..., on clinical symptomatology, sleep and anxiety of 45 patients with insomnia based on a mild to moderate generalized anxiety disorder (GAD) (ICD-9 code: 307.42-1, 300,0; ASDC-APSS-Code: A.2.a), we compared, in a first step at baseline, drug-free polysomnographic and psychometric data of 22 patients recorded...

... generalized anxiety disordered patients collected two consecutive urines for measurement of 5-HIAA. The correlation of the 5-HIAA collections was r = 0.82, p = 0.0001. 22 2 2008 © 1994 S. Karger AG, Basel 1994 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

... patients with generalized anxiety disorder (GAD). In addition to evaluating overall efficacy in the composite patient data base, four criteria were used to identify subsets of patients with GAD who had coexisting depressive symptoms of at least moderate intensity: (1) a score of ≧ 2 on the Hamilton Anxiety...

... in double-blind and crossover conditions with the standard tablets of the same compound. 5 inpatients with generalized anxiety disorder received at 1-week intervals a single 30 mg dose of one of the compounds. Every 8 min for 96 min after drug intake, they completed a battery of visual analogue scales...

... changes at baseline, 4 h, 1 week and 14 days of treatment. The results indicate that patients with generalized anxiety disorder treated with bromazepam developed decreased skin conductance during the presentation of visual, auditory, and tactile stimuli presentations. Such skin conductance changes were...

...Giulio Perugi; Franco Frare; Cristina Toni; Giuseppe Ruffolo; Carlo Torti In a setting of routine clinical practice, 32 outpatients with generalized anxiety disorder (GAD) and major depression (MD) (n = 21) or dysthymia (n = 11), according to DSM-IV criteria, were consecutively treated...

... of relief from anxiety in humans. In the present study, EEGs were recorded, and the Hamilton Rating Scale for Anxiety and the state anxiety scale of Spielberger’s State-Trait Anxiety Inventory were evaluated once a week in 28 patients with generalized anxiety disorder. The Taylor Manifest Anxiety Scale...