...Miriam Sebold; Stefan J. Kiebel; Michael N. Smolka; Andreas Heinz; Lorenz Deserno Alcohol use disorder (AUD) is characterized by a combination of symptoms including excessive craving, loss of control, and progressive neglect of alternative pleasures. A mechanistic understanding of what drives...

...-alpha-reductase 2 (SRD5A2) V89L polymorphism are associated with craving during alcohol withdrawal, but little is known about their impact on symptomatology of opioid dependence. Methods: In this study, we analyzed 2 independent male cohorts of opioid-dependent patients for possible alterations...

...Nina Romanczuk-Seiferth; Wim van den Brink; Anna E. Goudriaan Pathological gambling (PG), as defined until recently in the DSM-IV, shares many clinical characteristics with substance use disorders (SUDs), such as craving and loss of control. Moreover, an increasing body of literature also revealed...

... levels were reduced. The ANP, AVP and cortisol serum levels were not significantly associated with the psychometric dimensions of heroin craving. In conclusion, chronic drug abuse profoundly alters stress-responsive systems like the HPA axis. Alterations of AVP, ANP and cortisol appear to constitute...

..., craving and psychiatric symptomatology were not significantly different between the opiate and cocaine addicts. Discussion: This is the first study evaluating the magnesium level in cocaine addicts. Cocaine addicts showed higher total plasma magnesium levels than opiate addicts and normal controls, even...

... and to examine the relationship between the power in each spectral bandwidth and subjective craving. Methods: EEG frequencies in response to a smoking-related and a neutral cue were examined in 23 smokers and 21 ex-smokers, who quit smoking for 1.4 years on average. Additionally, self-report measures...

...Verner J. Knott; Luma Naccache; Emmanuelle Cyr; Derek J. Fisher; Judy F. McIntosh; Anne M. Millar; Crystal M. Villeneuve Background/Aims: Cigarette craving is a core symptom of smoking withdrawal, which is more intense and more frequently observed in smokers with depressed mood. Using self-reports...

...M. Corominas; C. Roncero; M. Ribases; X. Castells; M. Casas Cocaine addiction is one of the severest health problems faced by western countries, where there is an increasing prevalence of lifelong abuse. The most challenging aspects in the treatment of cocaine addiction are craving and relapse...

...), Bech-Rafaelsen Melancholia Scale (BRMS), Scale for the Assessment of Negative Symptoms (SANS), specific withdrawal scales, and visual analogue scales (VAS) for hedonic capability and substance craving. The scales measuring anhedonia either directly (SHAPS, VAS for hedonic capability) or in some key...

...Giovanni Addolorato; Ludovico Abenavoli; Lorenzo Leggio; Giovanni Gasbarrini In the last decade, craving has increasingly been considered an important target for the treatment of patients with alcohol problems, and several drugs able to interfere with the neurotransmitters involved in craving...

... in the past, heroin craving and these EEG measures were studied. The results show that heroin-dependent subjects have increased relative beta-2 power and increased left intrahemispheric gamma coherence compared with control subjects. Furthermore, coherence measures showed correlations with clinical variables...

...Sonnig S.W. Chiang; Christian G. Schuetz; Michael Soyka Objective: Irritability is often linked with problem drinking. The aim of this study is to examine the possible influence of irritability on craving induced by a cue-exposure paradigm. Methods: 30 male abstinent alcoholic inpatients...